Literature DB >> 18181948

Anthropological and ethical reflections on the production and use of embryonic stem cells.

M P Faggioni1.   

Abstract

Stem cells and their potential therapeutic application have generated tremendous public interest, great enthusiasm among researchers and intense commercial interest. There are diverse sources of stem cells. According to their origin and their biological characteristics, they are classified as embryonic stem cells, germline stem cells and tissue stem cells. Until now, the most concrete therapeutic results have come from some adult tissue stem cells, with promising prospects also being offered by umbilical cord stem cells. Regarding embryonic stem cells, there is concern that they would be difficult to control in vivo. Nonetheless, many researchers are still pursuing their potential uses, convinced that they will be useful not only for study, but also for therapy, especially as a result of their high capacity for self-renewal as well as their broad potential for differentiation. This discussion which is eminently scientific in nature, and not lacking in ethical and political repercussions, will not be entered into above all regarding the allocation of available intellectual and economic resources.

Mesh:

Year:  2008        PMID: 18181948      PMCID: PMC6496030          DOI: 10.1111/j.1365-2184.2008.00489.x

Source DB:  PubMed          Journal:  Cell Prolif        ISSN: 0960-7722            Impact factor:   6.831


  5 in total

1.  Putting stem cells to work.

Authors:  D Solter; J Gearhart
Journal:  Science       Date:  1999-03-05       Impact factor: 47.728

2.  Human eggs supply 'ethical' stem cells.

Authors:  Jo Marchant
Journal:  Nature       Date:  2006-06-29       Impact factor: 49.962

3.  Human embryonic stem cell lines derived from single blastomeres.

Authors:  Irina Klimanskaya; Young Chung; Sandy Becker; Shi-Jiang Lu; Robert Lanza
Journal:  Nature       Date:  2006-08-23       Impact factor: 49.962

4.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

5.  Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts.

Authors:  Alexander Meissner; Rudolf Jaenisch
Journal:  Nature       Date:  2005-10-16       Impact factor: 49.962

  5 in total
  1 in total

Review 1.  Science and ethics: bridge to the future for regenerative medicine.

Authors:  Ventura-Juncá Patricio
Journal:  Int J Stem Cells       Date:  2011-11       Impact factor: 2.500

  1 in total

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