Literature DB >> 24298338

Science and ethics: bridge to the future for regenerative medicine.

Ventura-Juncá Patricio1.   

Abstract

The objective of this article is to reflect on the relationship between regenerative medicine and ethics, using as references the Aristotelian concept of what is ethical and that of Raessler Van Potter about bioethics. To do this, I will briefly describe the advances in regenerative medicine with stem cells, the strategies for producing pluripotential cells without destroying human embryos, and the great potential of stem cells to improve life for Humanity, noting that for this to be possible, it is necessary to locate the role of regenerative medicine in the context of human values and well being. In this way, this article has a real perspective of the role that regenerative medicine can play in benefitting human beings and engendering respect for human and natural environments.

Entities:  

Keywords:  Bioethics; Regenerative medicine; Science and human values; Stem cells

Year:  2011        PMID: 24298338      PMCID: PMC3840959          DOI: 10.15283/ijsc.2011.4.2.79

Source DB:  PubMed          Journal:  Int J Stem Cells        ISSN: 2005-3606            Impact factor:   2.500


  31 in total

Review 1.  Prometheus's vulture and the stem-cell promise.

Authors:  Nadia Rosenthal
Journal:  N Engl J Med       Date:  2003-07-17       Impact factor: 91.245

2.  Allowing innovative stem cell-based therapies outside of clinical trials: ethical and policy challenges.

Authors:  Insoo Hyun
Journal:  J Law Med Ethics       Date:  2010       Impact factor: 1.718

3.  Production of pluripotent stem cells by oocyte-assisted reprogramming: joint statement with signatories.

Authors:  Hadley Arkes; Nicanor Pier Giorgio Austriaco; Thomas Berg; E Christian Brugger; Nigel M de S Cameron; Joseph Capizzi; Maureen L Condic; Samuel B Condic; Kevin T FitzGerald; Kevin Flannery; Edward J Furton; Robert P George; Timothy George; Alfonso Gomez-Lobo; Germain Grisez; Markus Grompe; John M Haas; Robert Hamerton-Kelly; John Collins Harvey; Paul J Hoehner; William B Hurlbut; John F Kilner; Patrick Lee; William E May; Gonzalo Miranda; C Ben Mitchell; John J Myers; Chris Oleson; Tad Pacholczyk; Peter F Ryan; William L Saunders; David Stevens; Stuart W Swetland; M Edward Whelan; Thomas Williams
Journal:  Natl Cathol Bioeth Q       Date:  2005

Review 4.  Ethical issues in stem cell research.

Authors:  Bernard Lo; Lindsay Parham
Journal:  Endocr Rev       Date:  2009-04-14       Impact factor: 19.871

Review 5.  Parthenogenetic cell lines: an unstable equilibrium between pluripotency and malignant transformation.

Authors:  Tiziana A L Brevini; Georgia Pennarossa; Magda deEguileor; Gianluca Tettamanti; Guido Ragni; Alessio Paffoni; Fulvio Gandolfi
Journal:  Curr Pharm Biotechnol       Date:  2011-02-01       Impact factor: 2.837

6.  Human embryonic stem cell lines derived from single blastomeres.

Authors:  Irina Klimanskaya; Young Chung; Sandy Becker; Shi-Jiang Lu; Robert Lanza
Journal:  Nature       Date:  2006-08-23       Impact factor: 49.962

7.  Two new protocols to enhance the production and isolation of human induced pluripotent stem cell lines.

Authors:  Emily Dick; Elena Matsa; Jayson Bispham; Mojgan Reza; Michela Guglieri; Andrew Staniforth; Sue Watson; Rajendra Kumari; Hanns Lochmüller; Lorraine Young; David Darling; Chris Denning
Journal:  Stem Cell Res       Date:  2010-11-20       Impact factor: 2.020

8.  Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin.

Authors:  Jacob Hanna; Marius Wernig; Styliani Markoulaki; Chiao-Wang Sun; Alexander Meissner; John P Cassady; Caroline Beard; Tobias Brambrink; Li-Chen Wu; Tim M Townes; Rudolf Jaenisch
Journal:  Science       Date:  2007-12-06       Impact factor: 47.728

9.  In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

Authors:  Marius Wernig; Alexander Meissner; Ruth Foreman; Tobias Brambrink; Manching Ku; Konrad Hochedlinger; Bradley E Bernstein; Rudolf Jaenisch
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

10.  Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.

Authors:  Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Keisuke Okita; Yuji Mochiduki; Nanako Takizawa; Shinya Yamanaka
Journal:  Nat Biotechnol       Date:  2007-11-30       Impact factor: 54.908

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