Literature DB >> 18175984

A new leishmanicidal saponin from Brunfelsia grandiflora.

Hiroyuki Fuchino1, Setsuko Sekita, Kanami Mori, Nobuo Kawahara, Motoyoshi Satake, Fumiyuki Kiuchi.   

Abstract

A new furostan-type saponin (1) was isolated from the methanolic extract of Brunfelsia grandiflora leaves, together with four known compounds. The chemical structure of 1 was determined by spectroscopic analysis and chemical reaction to be 26-O-beta-D-glucopyranosyl 22alpha-methoxyfurost-3beta,26-diol 3-O-beta-D-xylopyranosyl(1-->3)-{beta-D-glucopyranosyl(1-->2)}-beta-D-glucopyranosyl(1-->4)-beta-D-glucopyranoside. Compound 1 showed potent leishmanicidal activity in vitro against Leishmania major.

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Year:  2008        PMID： 18175984     DOI： 10.1248/cpb.56.93

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  6 in total

1.  Leishmanicidal activity of saponins isolated from the leaves of Eclipta prostrata and Gymnema sylvestre.

Authors:  Venkatesan Gopiesh Khanna; Krishnan Kannabiran; Giulia Getti
Journal:  Indian J Pharmacol       Date:  2009-02       Impact factor: 1.200

2.  The efficacy of 2-nitrovinylfuran derivatives against Leishmania in vitro and in vivo.

Authors:  Sergio Sifontes-Rodríguez; Lianet Monzote-Fidalgo; Nilo Castañedo-Cancio; Ana Margarita Montalvo-Álvarez; Yamilé López-Hernández; Niurka Mollineda Diogo; Juan Francisco Infante-Bourzac; Oliver Pérez-Martín; Alfredo Meneses-Marcel; José Antonio Escario García-Trevijano; Miguel Ángel Cabrera-Pérez
Journal:  Mem Inst Oswaldo Cruz       Date:  2015-03-24       Impact factor: 2.743

3.  Chiricaspi (Brunfelsia grandiflora, Solanaceae), a Pharmacologically Promising Plant.

Authors:  Carmen X Luzuriaga-Quichimbo; Míriam Hernández Del Barco; José Blanco-Salas; Carlos E Cerón-Martínez; Trinidad Ruiz-Téllez
Journal:  Plants (Basel)       Date:  2018-08-18

4.  Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species.

Authors:  Myrna Adianti; Chie Aoki; Mari Komoto; Lin Deng; Ikuo Shoji; Tutik Sri Wahyuni; Maria Inge Lusida; Hiroyuki Fuchino; Nobuo Kawahara; Hak Hotta
Journal:  Microbiol Immunol       Date:  2014-03       Impact factor: 1.955

5.  Identification, Quantification, and Characterization of the Phenolic Fraction of Brunfelsia grandiflora: In Vitro Antioxidant Capacity.

Authors:  Raquel Mateos; Norma Ramos-Cevallos; Americo Castro-Luna; Mariella Ramos-Gonzalez; Zoyla-Mirella Clavo; Miguel Quispe-Solano; Luis Goya; José-Luis Rodríguez
Journal:  Molecules       Date:  2022-10-02       Impact factor: 4.927

6.  Promising Potential of Lonchocarpus utilis against South American Myasis.

Authors:  Carmen X Luzuriaga-Quichimbo; José Blanco-Salas; Carlos E Cerón-Martínez; Juan Carlos Alías-Gallego; Trinidad Ruiz-Téllez
Journal:  Plants (Basel)       Date:  2019-12-25
  6 in total

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