| Literature DB >> 18171158 |
James F Parham1, Randall B Irmis.
Abstract
We reassess a study on a fossil-calibrated molecular clock that provides a new method for evaluating the accuracy of calibration points. We address several pitfalls that molecular systematists should be aware of when calculating rates of molecular evolution based on fossil calibrations. These caveats involve the substantiation and accurate use of geologic dates, the inappropriate use of fixed calibration points, and the explicit and objective phylogenetic placement of fossil taxa. Paleontological data, like molecular data, should be treated with the utmost rigor.Mesh:
Year: 2008 PMID: 18171158 DOI: 10.1086/524198
Source DB: PubMed Journal: Am Nat ISSN: 0003-0147 Impact factor: 3.926