OBJECTIVE: To determine whether pronuclear morphology is a useful additional criterion when selecting embryos for transfer. METHOD: A modified Tesarik and Greco scoring system was used in this retrospective study to assess the pronuclear morphology of 883 zygotes from 214 in vitro fertilization or intracytoplasmic sperm injection cycles. Pronucleus size and presence of cytoplasmic halo were also noted. Embryo selection was performed on Day 2 or 3 following oocyte retrieval. The chi2, analysis of variance, Kruskal-Wallis, and Fisher exact tests were used where appropriate. RESULTS: A stepwise logistic regression revealed that a better embryo quality was associated with both pattern 0 of the scoring system and pronuclei of equal size on Days 2 or 3. Higher pregnancy and multiple gestation rates were obtained when at least 1 embryo classified as pattern 0 was included in the set of embryos transferred. CONCLUSION: Combined with embryo morphology evaluation on Days 2 and 3, a scoring system based on pronuclear morphology seems to provide a good criterion when selecting embryos for transfer.
OBJECTIVE: To determine whether pronuclear morphology is a useful additional criterion when selecting embryos for transfer. METHOD: A modified Tesarik and Greco scoring system was used in this retrospective study to assess the pronuclear morphology of 883 zygotes from 214 in vitro fertilization or intracytoplasmic sperm injection cycles. Pronucleus size and presence of cytoplasmic halo were also noted. Embryo selection was performed on Day 2 or 3 following oocyte retrieval. The chi2, analysis of variance, Kruskal-Wallis, and Fisher exact tests were used where appropriate. RESULTS: A stepwise logistic regression revealed that a better embryo quality was associated with both pattern 0 of the scoring system and pronuclei of equal size on Days 2 or 3. Higher pregnancy and multiple gestation rates were obtained when at least 1 embryo classified as pattern 0 was included in the set of embryos transferred. CONCLUSION: Combined with embryo morphology evaluation on Days 2 and 3, a scoring system based on pronuclear morphology seems to provide a good criterion when selecting embryos for transfer.
Authors: Alessia Nicoli; Francesco Capodanno; Lucia Moscato; Ilaria Rondini; Maria T Villani; Antonella Tuzio; Giovanni B La Sala Journal: Reprod Biol Endocrinol Date: 2010-06-25 Impact factor: 5.211
Authors: Alessia Nicoli; Stefano Palomba; Francesco Capodanno; Maria Fini; Angela Falbo; Giovanni Battista La Sala Journal: J Ovarian Res Date: 2013-09-12 Impact factor: 4.234
Authors: Alessia Nicoli; Francesco Capodanno; Ilaria Rondini; Barbara Valli; Maria Teresa Villani; Daria Morini; Leonardo De Pascalis; Stefano Palomba; Giovanni Battista La Sala Journal: J Ovarian Res Date: 2013-01-03 Impact factor: 4.234
Authors: Cristina Álvarez; Carmen García-Garrido; Roser Taronger; Gaspar González de Merlo Journal: Indian J Med Res Date: 2013-02 Impact factor: 2.375