Literature DB >> 18164197

Antimitotic quinoid triterpenes from Maytenus chuchuhuasca.

Hiroshi Morita1, Yusuke Hirasawa, Akihiro Muto, Tadashi Yoshida, Setsuko Sekita, Osamu Shirota.   

Abstract

Four cytotoxic quinoid triterpenes, tingenone (1), 22 beta-hydroxytingenone (2), pristimerin (3), and celastrol (4), isolated from Maytenus chuchuhuasca, potently inhibit the polymerization of tubulin.

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Year:  2007        PMID： 18164197     DOI： 10.1016/j.bmcl.2007.12.016

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  7 in total

1.  Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells.

Authors:  Radhamani Kannaiyan; Hui Sin Hay; Peramaiyan Rajendran; Feng Li; Muthu K Shanmugam; Shireen Vali; Taher Abbasi; Shweta Kapoor; Ashish Sharma; Alan Prem Kumar; Wee-Joo Chng; Gautam Sethi
Journal:  Br J Pharmacol       Date:  2011-11       Impact factor: 8.739

Review 2.  Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents.

Authors:  Reen-Yen Kuo; Keduo Qian; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal:  Nat Prod Rep       Date:  2009-08-13       Impact factor: 13.423

3.  HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way.

Authors:  Bin Peng; Limin Xu; Fanfan Cao; Tingxuan Wei; Chunxin Yang; Georges Uzan; Denghai Zhang
Journal:  Mol Cancer       Date:  2010-04-16       Impact factor: 27.401

4.  Pristimerin Inhibits LPS-Triggered Neurotoxicity in BV-2 Microglia Cells Through Modulating IRAK1/TRAF6/TAK1-Mediated NF-κB and AP-1 Signaling Pathways In Vitro.

Authors:  Bin Hui; Liping Zhang; Qinhua Zhou; Ling Hui
Journal:  Neurotox Res       Date:  2017-11-08       Impact factor: 3.911

5.  MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.

Authors:  Zhixiang Zhang; Tao Meng; Jingxue He; Ming Li; Lin-Jiang Tong; Bing Xiong; Liping Lin; Jingkang Shen; Ze-Hong Miao; Jian Ding
Journal:  Invest New Drugs       Date:  2009-08-25       Impact factor: 3.850

6.  Production of the quinone-methide triterpene maytenin by in vitro adventitious roots of Peritassa campestris (Cambess.) A.C.Sm. (Celastraceae) and rapid detection and identification by APCI-IT-MS/MS.

Authors:  Tiago Antunes Paz; Vânia A F F M dos Santos; Marielle Cascaes Inácio; Edieidia Souza Pina; Ana Maria Soares Pereira; Maysa Furlan
Journal:  Biomed Res Int       Date:  2013-09-25       Impact factor: 3.411

7.  SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii.

Authors:  Young Bae Ryu; Su-Jin Park; Young Min Kim; Ju-Yeon Lee; Woo Duck Seo; Jong Sun Chang; Ki Hun Park; Mun-Chual Rho; Woo Song Lee
Journal:  Bioorg Med Chem Lett       Date:  2010-02-04       Impact factor: 2.823
  7 in total

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