Literature DB >> 18154610

Special regulatory T cell review: How I became a T suppressor/regulatory cell maven.

Ethan M Shevach1.   

Abstract

I have briefly reviewed the factors that motivated me to change my views about the existence and importance of suppressor/regulatory T cells and to devote the majority of my laboratory efforts to this newly revitalized area of immunologic research. I am optimistic that manipulation of regulatory T-cell function will shortly be applicable to the clinic.

Mesh:

Year:  2008        PMID: 18154610      PMCID: PMC2433279          DOI: 10.1111/j.1365-2567.2007.02777.x

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  11 in total

1.  CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells.

Authors:  E Suri-Payer; A Z Amar; A M Thornton; E M Shevach
Journal:  J Immunol       Date:  1998-02-01       Impact factor: 5.422

2.  Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.

Authors:  S Sakaguchi; N Sakaguchi; M Asano; M Itoh; M Toda
Journal:  J Immunol       Date:  1995-08-01       Impact factor: 5.422

Review 3.  Post-thymectomy autoimmunity: abnormal T-cell homeostasis.

Authors:  A Bonomo; P J Kehn; E M Shevach
Journal:  Immunol Today       Date:  1995-02

4.  Isolation of cDNA clones encoding T cell-specific membrane-associated proteins.

Authors:  S M Hedrick; D I Cohen; E A Nielsen; M M Davis
Journal:  Nature       Date:  1984 Mar 8-14       Impact factor: 49.962

5.  Post-thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells.

Authors:  E Suri-Payer; A Z Amar; R McHugh; K Natarajan; D H Margulies; E M Shevach
Journal:  Eur J Immunol       Date:  1999-02       Impact factor: 5.532

6.  Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.

Authors:  T R Malek; R J Robb; E M Shevach
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

7.  RNA transcripts for I-J polypeptides are apparently not encoded between the I-A and I-E subregions of the murine major histocompatibility complex.

Authors:  M Kronenberg; M Steinmetz; J Kobori; E Kraig; J A Kapp; C W Pierce; C M Sorensen; G Suzuki; T Tada; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

8.  Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice.

Authors:  Y Nishizuka; T Sakakura
Journal:  Science       Date:  1969-11-07       Impact factor: 47.728

9.  Certified professionals: CD4(+)CD25(+) suppressor T cells.

Authors:  E M Shevach
Journal:  J Exp Med       Date:  2001-06-04       Impact factor: 14.307

10.  CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production.

Authors:  A M Thornton; E M Shevach
Journal:  J Exp Med       Date:  1998-07-20       Impact factor: 14.307

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  7 in total

Review 1.  Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target.

Authors:  Dorothy K Sojka; Yu-Hui Huang; Deborah J Fowell
Journal:  Immunology       Date:  2008-03-14       Impact factor: 7.397

Review 2.  Tregs: hype or hope for allogeneic hematopoietic stem cell transplantation?

Authors:  F Lussana; M Di Ianni; A Rambaldi
Journal:  Bone Marrow Transplant       Date:  2017-03-20       Impact factor: 5.483

3.  Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation.

Authors:  Yannick D Muller; Gang Mai; Philippe Morel; Véronique Serre-Beinier; Carmen Gonelle-Gispert; Gisella Puga Yung; Driss Ehirchiou; Jean-Christophe Wyss; Sinda Bigenzahn; Magali Irla; Christoph Heusser; Déla Golshayan; Jörg D Seebach; Thomas Wekerle; Leo H Bühler
Journal:  PLoS One       Date:  2010-04-26       Impact factor: 3.240

Review 4.  Vaccines for pancreatic cancer.

Authors:  Kevin C Soares; Lei Zheng; Barish Edil; Elizabeth M Jaffee
Journal:  Cancer J       Date:  2012 Nov-Dec       Impact factor: 3.360

Review 5.  Regulatory immunotherapy in bone marrow transplantation.

Authors:  Vanessa Morales-Tirado; Wioleta Luszczek; Marié van der Merwe; Asha Pillai
Journal:  ScientificWorldJournal       Date:  2012-01-02

6.  Limosilactobacillus reuteri and Lacticaseibacillus rhamnosus GG differentially affect gut microbes and metabolites in mice with Treg deficiency.

Authors:  Yuying Liu; Thomas K Hoang; Christopher M Taylor; Evelyn S Park; Jasmin Freeborn; Meng Luo; Stefan Roos; J Marc Rhoads
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2021-03-31       Impact factor: 4.871

7.  Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression.

Authors:  Timothy R D J Radstake; Lenny van Bon; Jasper Broen; Mark Wenink; Kim Santegoets; Yanhui Deng; Anila Hussaini; Robert Simms; William W Cruikshank; Robert Lafyatis
Journal:  PLoS One       Date:  2009-06-22       Impact factor: 3.240

  7 in total

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