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Literature DB >> 18152339

The role of the wax of the tubercle bacillus in establishing delayed hypersensitivity, hypersensitivity to a protein antigen, egg albumin.

Abstract

Guinea pigs sensitized with egg albumin along with the purified wax fraction of the human tubercle bacillus respond with delayed hypersensitive reactivity to the protein antigen. Previous publications have reported a similar activity of the wax with respect to tuberculoprotein and picryl chloride. The effect is not referable to an ordinary adjuvant activity of the bacillary wax, since antibody titers are not increased in animals which receive it, and since a known adjuvant, water-in-oil emulsion, has no effect with respect to the induction of delayed hypersensitivity. This report further extends the rôle of the tubercle bacillary wax in the induction of delayed hypersensitive states.

Entities: Chemical Disease Species

Keywords: TUBERCLE BACILLI; TUBERCULOSIS/antigens and antibodies

Mesh：

Substances：

Year: 1949 PMID： 18152339 PMCID： PMC2135935 DOI： 10.1084/jem.90.1.53

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

8 in total

1. Corneal Reactions of Normal and of Tuberculous Guinea Pigs to Tuberculo-Protein and Tuberculo-Phosphatide.

Authors: S W Holley
Journal: Am J Pathol Date: 1935-11 Impact factor: 4.307

2. TISSUE CULTURE STUDIES ON BACTERIAL HYPERSENSITIVITY : I. TUBERCULIN SENSITIVE TISSUES.

Authors: J K Moen; H F Swift
Journal: J Exp Med Date: 1936-08-31 Impact factor: 14.307

3. CELLULAR REACTIONS TO WAX-LIKE MATERIALS FROM ACID-FAST BACTERIA : THE UNSAPONIFIABLE FRACTION FROM THE TUBERCLE BACILLUS, STRAIN H-37.

Authors: F R Sabin; K C Smithburn; R M Thomas
Journal: J Exp Med Date: 1935-11-30 Impact factor: 14.307

4. THE SPECIFIC CYTOTOXIC ACTION OF TUBERCULIN IN TISSUE CULTURE.

Authors: J D Aronson
Journal: J Exp Med Date: 1931-07-31 Impact factor: 14.307

5. STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS : VII. SKIN SENSITIZATION BY INTRAPERITONEAL INJECTIONS.

Authors: K Landsteiner; M W Chase
Journal: J Exp Med Date: 1940-01-31 Impact factor: 14.307

6. TISSUE CULTURE STUDIES ON BACTERIAL HYPERSENSITIVITY : II. REACTIONS OF TISSUES FROM GUINEA PIGS INFECTED WITH GROUP C HEMOLYTIC STREPTOCOCCI.

Authors: J K Moen
Journal: J Exp Med Date: 1936-08-31 Impact factor: 14.307

7. The role of the wax of the tubercle bacillus in establishing delayed hypersensitivity; hypersensitivity to a simple chemical substance, picryl chloride.

Authors: S RAFFEL; J E FORNEY
Journal: J Exp Med Date: 1948-10-01 Impact factor: 14.307

8. REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI : I. GENERAL TUBERCULIN-LIKE HYPERSENSITIVENESS, ALLERGY, OR HYPERERGY FOLLOWING THE SECONDARY REACTION.

Authors: C L Derick; H F Swift
Journal: J Exp Med Date: 1929-03-31 Impact factor: 14.307

8 in total

9 in total

Review 5. [Adjuvant effect of mycobacteria].

Authors: H Finger
Journal: Klin Wochenschr Date: 1966-10-01

6. IN VITRO STUDIES OF CELLULAR HYPERSENSITIVITY. II. RELATIONSHIP OF DELAYED HYPERSENSITIVITY AND INHIBITION OF CELL MIGRATION BY PICRYLATED PROTEINS.

Authors: R R CARPENTER; M W BRANDRISS
Journal: J Exp Med Date: 1964-12-01 Impact factor: 14.307

7. Studies on the immunological response to foreign tumor transplants in the mouse. II. The relation between hemagglutinating antibody and graft resistance in the normal mouse and mice pretreated with tissue preparations.

Authors: N A MTTCHISON; O L DUBE
Journal: J Exp Med Date: 1955-08-01 Impact factor: 14.307

8. The delayed hypersensitivity induced by antigen-antibody complexes.

Authors: S RAFFEL; J M NEWEL
Journal: J Exp Med Date: 1958-12-01 Impact factor: 14.307

9. Elicitation of allergic contact dermatitis in the guinea pig; the distribution of bound dinitrobenzene groups within the skin and quantitative determination of the extent of combination of 2,4-dinitro-chlorobenzene with epidermal protein in vivo.

Authors: H N EISEN; M TABACHNICK
Journal: J Exp Med Date: 1958-12-01 Impact factor: 14.307