| Literature DB >> 19870959 |
Abstract
A method has been described by which sensitization to a simple chemical, picryl chloride (2:4:6 trinitrochlorobenzene), can be satisfactorily attained by means of intraperitoneal injection of the compound when killed tubercle bacilli suspended in paraffin oil were used as adjuvant. Sensitivity of the contact dermatitis type results therefrom. It follows that although skin sensitization of this type is most easily obtained by dermal application this route of administration is no necessary condition for such sensitivity.Entities:
Year: 1940 PMID: 19870959 PMCID: PMC2135072 DOI: 10.1084/jem.71.2.237
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307