Literature DB >> 1812793

Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry.

M A Moseley1, L J Deterding, K B Tomer, J W Jorgenson.   

Abstract

Mixtures of bioactive peptides have been analyzed by capillary zone electrophoresis/mass spectrometry (CZE/MS) using an on-line coaxial continuous-flow fast atom bombardment interface. High separation efficiencies (up to 410,000 theoretical plates) were obtained from low femtomole levels of peptides. The analysis of basic peptides was accomplished by using aminopropyl-silylated CZE columns to minimize zone broadening due to adsorption effects. CZE/MS/MS data were acquired from femtomole levels of peptides in electrophoretic real time.

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Year:  1991        PMID： 1812793     DOI： 10.1021/ac00002a005

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  7 in total

1.  Optimization of capillary zone electrophoresis/electrospray ionization parameters for the mass spectrometry and tandem mass spectrometry analysis of peptides.

Authors:  M A Moseley; J W Jorgenson; J Shabanowitz; D F Hunt; K B Tomer
Journal:  J Am Soc Mass Spectrom       Date:  1992-05       Impact factor: 3.109

2.  Application of nanoscale packed capillary liquid chromatography (75 μm id) and capillary zone electrophoresis/electrospray ionization mass spectrometry to the analysis of macrolide antibiotics.

Authors:  C E Parker; J R Perkins; K B Tomer; Y Shida; K O'Hara; M Kono
Journal:  J Am Soc Mass Spectrom       Date:  1992-07       Impact factor: 3.109

3.  A Mass Spectrometer in Every Fume Hood.

Authors:  Ethan M McBride; Guido F Verbeck
Journal:  J Am Soc Mass Spectrom       Date:  2018-06-07       Impact factor: 3.109

Review 4.  Applications of capillary electrophoresis in pharmaceutical analysis.

Authors:  S R Rabel; J F Stobaugh
Journal:  Pharm Res       Date:  1993-02       Impact factor: 4.200

5.  Identification of deoxynucleoside-polyaromatic hydrocarbon adducts by capillary zone electrophoresis-Continuous Flow-fast atom bombardment mass spectrometry.

Authors:  S M Wolf; P Vouros; C Norwood; E Jackim
Journal:  J Am Soc Mass Spectrom       Date:  1992-10       Impact factor: 3.109

6.  Nanoscale separations combined with electrospray ionization mass spectrometry: Sulfonamide determination.

Authors:  J R Perkins; C E Parker; K B Tomer
Journal:  J Am Soc Mass Spectrom       Date:  1992-02       Impact factor: 3.109

7.  Spin-trapped Radicals: Determination by LC-TSP-MS and LC-ESI-MS.

Authors:  C E Parker; H Iwahashi; K B Tomer
Journal:  J Am Soc Mass Spectrom       Date:  1991-09       Impact factor: 3.109
  7 in total

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