Literature DB >> 18123178

The nature of the virus receptors of red cells; partial purification of the virus agglutination inhibitor in human plasma.

G K HIRST.   

Abstract

A substance (VHI) exists in human plasma which inhibits the agglutination of red cells by influenza virus and is distinct from influenza antibody. When plasma is fractionated by alcohol in the cold the VHI comes out mainly with a mixture of lipid-free alpha and beta globulins (fraction IV-4). On further fractionation the activity comes out with a fraction consisting mainly of beta(1) globulin (fraction IV-7). Boiling fraction IV-4 or IV-7 after considerable dilution brings about a large increase in the amount of VHI, much more than can be detected in the original plasma. A similar VHI has been extracted from the ghosts of fowl red cells.

Entities:  

Keywords:  VIRUSES

Mesh:

Substances:

Year:  1949        PMID: 18123178      PMCID: PMC2135861          DOI: 10.1084/jem.89.2.223

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  10 in total

1.  Seromucoid and the bound carbohydrate of the serum proteins.

Authors:  C Rimington
Journal:  Biochem J       Date:  1940-06       Impact factor: 3.857

2.  Studies in immunochemistry: 7. The isolation from hog gastric mucin of the polysaccharide-amino acid complex possessing blood group A specificity.

Authors:  W T Morgan; H K King
Journal:  Biochem J       Date:  1943       Impact factor: 3.857

3.  ADSORPTION OF INFLUENZA HEMAGGLUTININS AND VIRUS BY RED BLOOD CELLS.

Authors:  G K Hirst
Journal:  J Exp Med       Date:  1942-08-01       Impact factor: 14.307

4.  IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : III. PROPERTIES OF PURIFIED BLOOD GROUP A SUBSTANCES FROM INDIVIDUAL HOG STOMACH LININGS.

Authors:  A Bendich; E A Kabat; A E Bezer
Journal:  J Exp Med       Date:  1946-05-31       Impact factor: 14.307

5.  IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : I. ESTIMATION OF A AND B ISOANTIBODIES IN HUMAN SERUM BY THE QUANTITATIVE PRECIPITIN METHOD.

Authors:  E A Kabat; A E Bezer
Journal:  J Exp Med       Date:  1945-09-01       Impact factor: 14.307

6.  The nature of the virus receptors of red cells; the effect of partial heat inactivation of influenza virus on the destruction of red cell receptors and the use of inactivated virus in the measurement of serum inhibitor.

Authors:  G K HIRST
Journal:  J Exp Med       Date:  1948-04-01       Impact factor: 14.307

7.  PREPARATION FROM HUMAN RED CELLS OF A SUBSTANCE INHIBITING VIRUS HEMAGGLUTINATION.

Authors:  P M Deburgh; P C Yu; C Howe; M Bovarnick
Journal:  J Exp Med       Date:  1948-01-01       Impact factor: 14.307

8.  The nature of the virus receptors of red cells; evidence on the chemical nature of the virus receptors of red cells and of the existence of a closely analogous substance in normal serum.

Authors:  G K HIRST
Journal:  J Exp Med       Date:  1948-04-01       Impact factor: 14.307

9.  The inactivation of biologically active proteins, and the virus of western equine encephalomyelitis by periodic acid.

Authors:  W F GOEBEL; P K OLITSKY; A C SAENZ
Journal:  J Exp Med       Date:  1948-05-01       Impact factor: 14.307

10.  IMMUNOCHEMICAL STUDIES ON BLOOD GROUPS : II. PROPERTIES OF THE BLOOD GROUP A SUBSTANCE FROM POOLS OF HOO STOMACHS AND OF SPECIFIC PRECIPITATES COMPOSED OF "A" SUBSTANCE AND HOMOLOGOUS HUMAN ANTIBODY.

Authors:  E A Kabat; A Bendich; A E Bezer
Journal:  J Exp Med       Date:  1946-05-31       Impact factor: 14.307

  10 in total
  7 in total

1.  [Myxovirus hemaggIutination tests with various erythrocyte types. Comparative quantitative studies under various conditions].

Authors:  B SCHMIDT; K GROSSGEBAUER
Journal:  Z Hyg Infektionskr       Date:  1959

2.  [Nonspecific inhibitory factors against influenza viruses in the normal serum of guinea pigs].

Authors:  H LIPPELT; W WIRTH
Journal:  Arch Gesamte Virusforsch       Date:  1959

3.  [Not Available].

Authors:  R DEIBEL
Journal:  Klin Wochenschr       Date:  1957-03-15

4.  A mucoprotein derived from human urine which reacts with influenza, mumps, and Newcastle disease viruses.

Authors:  I TAMM; F L HORSFALL
Journal:  J Exp Med       Date:  1952-01       Impact factor: 14.307

5.  Receptor destruction by viruses of the mumps-NDV-influenza group.

Authors:  G K HIRST
Journal:  J Exp Med       Date:  1950-02       Impact factor: 14.307

6.  Influenza virus and its mucoprotein substrate in the chorioallantoic membrane of the chick embryo. I. Characterization and quantitative assay of soluble substrate and studies on its relation to allantoic cells.

Authors:  R W SCHLESINGER; H V KARR
Journal:  J Exp Med       Date:  1956-03-01       Impact factor: 14.307

7.  The nature of the virus receptors of red cells; effect of sodium periodate on the elution of influenza virus from red cells.

Authors:  G K HIRST
Journal:  J Exp Med       Date:  1949-02       Impact factor: 14.307

  7 in total

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