Literature DB >> 18096809

Cognitive recovery in socially deprived young children: the Bucharest Early Intervention Project.

Charles A Nelson1, Charles H Zeanah, Nathan A Fox, Peter J Marshall, Anna T Smyke, Donald Guthrie.   

Abstract

In a randomized controlled trial, we compared abandoned children reared in institutions to abandoned children placed in institutions but then moved to foster care. Young children living in institutions were randomly assigned to continued institutional care or to placement in foster care, and their cognitive development was tracked through 54 months of age. The cognitive outcome of children who remained in the institution was markedly below that of never-institutionalized children and children taken out of the institution and placed into foster care. The improved cognitive outcomes we observed at 42 and 54 months were most marked for the youngest children placed in foster care. These results point to the negative sequelae of early institutionalization, suggest a possible sensitive period in cognitive development, and underscore the advantages of family placements for young abandoned children.

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Year:  2007        PMID: 18096809     DOI: 10.1126/science.1143921

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  280 in total

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3.  The Bucharest Early Intervention Project: case study in the ethics of mental health research.

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9.  Early deprivation, atypical brain development, and internalizing symptoms in late childhood.

Authors:  J Bick; N Fox; C Zeanah; C A Nelson
Journal:  Neuroscience       Date:  2015-09-16       Impact factor: 3.590

10.  Prenatal cerebral ischemia disrupts MRI-defined cortical microstructure through disturbances in neuronal arborization.

Authors:  Justin M Dean; Evelyn McClendon; A Roger Hohimer; Christopher D Kroenke; Kelly Hansen; Aryan Azimi-Zonooz; Kevin Chen; Art Riddle; Xi Gong; Elica Sharifnia; Matthew Hagen; Tahir Ahmad; Lindsey A Leigland; Stephen A Back
Journal:  Sci Transl Med       Date:  2013-01-16       Impact factor: 17.956

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