Literature DB >> 18096496

Jekyll & Hyde: evolution of a superfamily.

Susan A Martinis1, Yan Ling Joy Pang.   

Abstract

Aminoacyl-tRNA synthetase mutations have been linked to neurological diseases, but aminoacylation may be unaffected. This protein superfamily also performs many other diverse functions. Yang et al. insightfully engineer a single mutation to unmask a cell signaling activity of tyrosyl-tRNA synthetase.

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Year:  2007        PMID: 18096496     DOI: 10.1016/j.chembiol.2007.12.001

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  5 in total

1.  Leucyl-tRNA synthetase-dependent and -independent activation of a group I intron.

Authors:  Michal T Boniecki; Seung Bae Rho; Mikhail Tukalo; Jennifer L Hsu; Eliana P Romero; Susan A Martinis
Journal:  J Biol Chem       Date:  2009-07-21       Impact factor: 5.157

2.  Duplication of leucyl-tRNA synthetase in an archaeal extremophile may play a role in adaptation to variable environmental conditions.

Authors:  Christopher S Weitzel; Li Li; Changyi Zhang; Kristen K Eilts; Nicholas M Bretz; Alex L Gatten; Rachel J Whitaker; Susan A Martinis
Journal:  J Biol Chem       Date:  2020-02-26       Impact factor: 5.157

Review 3.  tRNA synthetase: tRNA aminoacylation and beyond.

Authors:  Yan Ling Joy Pang; Kiranmai Poruri; Susan A Martinis
Journal:  Wiley Interdiscip Rev RNA       Date:  2014-04-04       Impact factor: 9.957

4.  Internally deleted human tRNA synthetase suggests evolutionary pressure for repurposing.

Authors:  Zhiwen Xu; Zhiyi Wei; Jie J Zhou; Fei Ye; Wing-Sze Lo; Feng Wang; Ching-Fun Lau; Jingjing Wu; Leslie A Nangle; Kyle P Chiang; Xiang-Lei Yang; Mingjie Zhang; Paul Schimmel
Journal:  Structure       Date:  2012-09-05       Impact factor: 5.006

5.  Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase.

Authors:  Zhiyi Wei; Zhiwen Xu; Xiaotian Liu; Wing-Sze Lo; Fei Ye; Ching-Fun Lau; Feng Wang; Jie J Zhou; Leslie A Nangle; Xiang-Lei Yang; Mingjie Zhang; Paul Schimmel
Journal:  Nucleic Acids Res       Date:  2016-01-14       Impact factor: 16.971

  5 in total

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