| Literature DB >> 18096496 |
Susan A Martinis1, Yan Ling Joy Pang.
Abstract
Aminoacyl-tRNA synthetase mutations have been linked to neurological diseases, but aminoacylation may be unaffected. This protein superfamily also performs many other diverse functions. Yang et al. insightfully engineer a single mutation to unmask a cell signaling activity of tyrosyl-tRNA synthetase.Entities:
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Year: 2007 PMID: 18096496 DOI: 10.1016/j.chembiol.2007.12.001
Source DB: PubMed Journal: Chem Biol ISSN: 1074-5521