Literature DB >> 18091492

Spinal cord injury in patients with ankylosing spondylitis: a 10-year review.

Pradeep Thumbikat1, Ramaswamy P Hariharan, Ganapathiraju Ravichandran, Martin R McClelland, Kidangalil M Mathew.   

Abstract

STUDY
DESIGN: Retrospective study.
OBJECTIVE: To evaluate the clinical and functional outcomes in patients with spinal cord injury (SCI) and preexisting ankylosing spondylitis (AS). SUMMARY OF BACKGROUND DATA: AS alters the strength and biomechanical properties of the spine that renders it susceptible to fracture with minimal trauma. Neurologic involvement is common and outcomes largely depend on the early recognition and appropriate management.
METHODS: A 10-year review (1996-2005) was carried out to identify all patients admitted with SCI associated with AS. The cause of injury, prehospital and emergency management, definitive treatment of fracture, final neurology, and functional outcomes were ascertained. Reasons for neurologic deterioration were determined.
RESULTS: Eighteen patients were identified. In 15 patients, the injury resulted from trauma (fall 14, road accident 1) and in 3 the SCI followed spinal surgical interventions. Twelve of the 15 patients with traumatic injuries were able to walk immediately after the fall but subsequently deteriorated for various reasons. Spinal epidural hematomas developed in 3 patients (2 traumatic, 1 spinal intervention). The fractures were managed surgically in 3 patients, halo jacket was used in 2, and the remainder were managed expectantly on traction. Four patients died before discharge, 4 were able to walk with an aid at discharge, and the others were wheel chair dependent.
CONCLUSION: Neurologic deficits were often subtle on initial presentation, resulting in many injuries being missed because of a low index of suspicion and poor visualization of lower cervical fractures on conventional radiographs. Extension of the ankylosed kyphotic cervical spine during conventional immobilization or for radiologic procedures resulted in neurologic deficits. Patients with an ankylosed cervical spine are normally unable to see the ceiling lying supine because of cervicothoracic kyphosis and use pillows to support their head. Cervical spine alignment in a similar flexed position is essential during immobilization or imaging. Medical alert cards as for patients with diabetes would be a way forward in correctly identifying patients with AS so that appropriate precautions can be instituted by emergency services.

Entities:  

Mesh:

Year:  2007        PMID: 18091492     DOI: 10.1097/BRS.0b013e31815cddfc

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  30 in total

1.  Ankylosing spondylitis with cervical fracture, cardiac arrest, locked-in syndrome and death.

Authors:  Sang Won Han; Sang Hyun Kim
Journal:  BMJ Case Rep       Date:  2012-07-10

Review 2.  Prehospital use of cervical collars in trauma patients: a critical review.

Authors:  Terje Sundstrøm; Helge Asbjørnsen; Samer Habiba; Geir Arne Sunde; Knut Wester
Journal:  J Neurotrauma       Date:  2013-11-06       Impact factor: 5.269

3.  [German Society for Rheumatology S3 guidelines on axial spondyloarthritis including Bechterew's disease and early forms: 8.6 Invasive therapy].

Authors:  U Kiltz; U Oberschelp; E Schneider; B Swoboda; H Böhm; M Winking; C Ulrich; J Braun
Journal:  Z Rheumatol       Date:  2014-09       Impact factor: 1.372

Review 4.  Pulmonary, renal and neurological comorbidities in patients with ankylosing spondylitis; implications for clinical practice.

Authors:  Cecilia Mercieca; Irene E van der Horst-Bruinsma; Andrew A Borg
Journal:  Curr Rheumatol Rep       Date:  2014-08       Impact factor: 4.592

5.  Fatality from minor cervical trauma in ankylosing spondylitis.

Authors:  Thorleif Etgen; Georg Rieder
Journal:  BMJ Case Rep       Date:  2009-05-21

Review 6.  Spondyloarthritis: clinical suspicion, diagnosis, and sports.

Authors:  Brock E Harper; John D Reveille
Journal:  Curr Sports Med Rep       Date:  2009 Jan-Feb       Impact factor: 1.733

Review 7.  Spinal fractures in patients with ankylosing spinal disorders: a systematic review of the literature on treatment, neurological status and complications.

Authors:  L A Westerveld; J J Verlaan; F C Oner
Journal:  Eur Spine J       Date:  2008-09-13       Impact factor: 3.134

8.  [Long version on the S3 guidelines for axial spondyloarthritis including Bechterew's disease and early forms, Update 2019 : Evidence-based guidelines of the German Society for Rheumatology (DGRh) and participating medical scientific specialist societies and other organizations].

Authors:  U Kiltz; J Braun; A Becker; J-F Chenot; M Dreimann; L Hammel; A Heiligenhaus; K-G Hermann; R Klett; D Krause; K-F Kreitner; U Lange; A Lauterbach; W Mau; R Mössner; U Oberschelp; S Philipp; U Pleyer; M Rudwaleit; E Schneider; T L Schulte; J Sieper; A Stallmach; B Swoboda; M Winking
Journal:  Z Rheumatol       Date:  2019-12       Impact factor: 1.372

9.  Two different causes of acute respiratory failure in a patient with diffuse idiopathic skeletal hyperostosis and ankylosed cervical spine.

Authors:  Rok Vengust; René Mihalic; Matjaz Turel
Journal:  Eur Spine J       Date:  2009-10-02       Impact factor: 3.134

10.  Surgical outcome after spinal fractures in patients with ankylosing spondylitis.

Authors:  George Sapkas; Konstantinos Kateros; Stamatios A Papadakis; Spyros Galanakos; Emmanuel Brilakis; George Machairas; Pavlos Katonis
Journal:  BMC Musculoskelet Disord       Date:  2009-08-02       Impact factor: 2.362

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