Literature DB >> 18084913

Drug discovery and development with plant-derived compounds.

Olivier Potterat1, Matthias Hamburger.   

Abstract

An overview is given on current efforts in drug development based on plant-derived natural products. Emphasis is on projects which have advanced to clinical development. Therapeutic areas covered include cancer, viral infections including HIV, malaria, inflammatory diseases, nociception and vaccine adjuvants, metabolic disorders, and neurodegenerative diseases. Aspects which are specific to plant-based drug discovery and development are also addressed, such as supply issues in the commercial development, and the Convention on Biological Diversity.

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Year:  2008        PMID： 18084913     DOI： 10.1007/978-3-7643-8117-2_2

Source DB:  PubMed          Journal:  Prog Drug Res        ISSN： 0071-786X


  10 in total

1.  Potentiation of the antitumor activity of adriamycin against osteosarcoma by cannabinoid WIN-55,212-2.

Authors:  Feng Niu; Song Zhao; Chang-Yan Xu; Hui Sha; Gui-Bin Bi; Lin Chen; Long Ye; Ping Gong; Tian-Hong Nie
Journal:  Oncol Lett       Date:  2015-07-23       Impact factor: 2.967

Review 2.  Database survey of anti-inflammatory plants in South America: a review.

Authors:  Gedson Rodrigues de Morais Lima; Camila de Albuquerque Montenegro; Cynthia Layse Ferreira de Almeida; Petrônio Filgueiras de Athayde-Filho; José Maria Barbosa-Filho; Leônia Maria Batista
Journal:  Int J Mol Sci       Date:  2011-04-21       Impact factor: 5.923

Review 3.  Amyloid beta-protein assembly as a therapeutic target of Alzheimer's disease.

Authors:  Ghiam Yamin; Kenjiro Ono; Mohammed Inayathullah; David B Teplow
Journal:  Curr Pharm Des       Date:  2008       Impact factor: 3.116

Review 4.  A call for using natural compounds in the development of new antimalarial treatments - an introduction.

Authors:  Hagai Ginsburg; Eric Deharo
Journal:  Malar J       Date:  2011-03-15       Impact factor: 2.979

5.  Antifungal, antibacterial and antimycobacterial activity of Entada abysinnica Steudel ex A. Rich (Fabaceae) methanol extract.

Authors:  Richard M Mariita; John A Orodho; Paul O Okemo; Paul K Mbugua
Journal:  Pharmacognosy Res       Date:  2010-05

6.  Effects of organic extracts and their different fractions of five Bangladeshi plants on in vitro thrombolysis.

Authors:  Talha Bin Emran; Md Atiar Rahman; Mir Muhammad Nasir Uddin; Md Mominur Rahman; Md Zia Uddin; Raju Dash; Chadny Layzu
Journal:  BMC Complement Altern Med       Date:  2015-04-23       Impact factor: 3.659

Review 7.  Natural product-derived drugs for the treatment of inflammatory bowel diseases.

Authors:  Young-Eun Joo
Journal:  Intest Res       Date:  2014-04-29

8.  An Integrated Computational Approach for Plant-Based Protein Tyrosine Phosphatase Non-Receptor Type 1 Inhibitors.

Authors:  Shabana Bibi; Katsumi Sakata
Journal:  Curr Comput Aided Drug Des       Date:  2017-11-10       Impact factor: 1.606

9.  Evaluation of antirotavirus activity of flavonoids.

Authors:  Luciane Anita Savi; Thiago Caon; Ana Paula de Oliveira; Andrea Michel Sobottka; Wolfgang Werner; Flávio Henrique Reginatto; Eloir Paulo Schenkel; Célia Regina Monte Barardi; Cláudia Maria Oliveira Simões
Journal:  Fitoterapia       Date:  2010-07-24       Impact factor: 2.882

10.  Azepanodipterocarpol is potential candidate for inhibits influenza H1N1 type among other lupane, oleanane, and dammarane A-ring amino-triterpenoids.

Authors:  Irina Smirnova; Anastasiya Petrova; Alexander Lobov; El'za Minnibaeva; Thao Tran Thi Phoung; Loc Tran Van; Myint Myint Khine; Iana Esaulkova; Alexander Slita; Vladimir Zarubaev; Oxana Kazakova
Journal:  J Antibiot (Tokyo)       Date:  2022-03-04       Impact factor: 3.424
  10 in total

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