Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Crystallization and preliminary crystallographic analysis of the Tob-hCaf1 complex.

Literature DB >> 18084094

Crystallization and preliminary crystallographic analysis of the Tob-hCaf1 complex.

Kinya Nishida¹, Masataka Horiuchi, Nobuo N Noda, Kiyohiro Takahasi, Norimasa Iwasaki, Akio Minami, Fuyuhiko Inagaki.

Abstract

The Tob/BTG family is a group of antiproliferative proteins that contain two highly homologous regions named Box A and Box B. These proteins all associate with CCR4-associated factor 1 (Caf1), which belongs to the ribonuclease D family of deadenylases. The antiproliferative region of human Tob (residues 1-138) and intact hCaf1 were co-expressed in Escherichia coli, purified and successfully cocrystallized. The crystal belongs to the tetragonal space group I422, with unit-cell parameters a = b = 150.9, c = 113.9 A, and is estimated to contain one heterodimer per asymmetric unit. The crystal diffracted to around 2.6 A resolution.

Entities: Gene Species

Mesh：

Substances：

Year: 2007 PMID： 18084094 PMCID： PMC2344109 DOI： 10.1107/S1744309107057466

Source DB: PubMed Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun ISSN： 1744-3091

20 in total

Review 1. Messenger RNA turnover in eukaryotes: pathways and enzymes.

Authors: Sylke Meyer; Claudia Temme; Elmar Wahle
Journal: Crit Rev Biochem Mol Biol Date: 2004 Jul-Aug Impact factor: 8.250

2. Structure and expression of TIS21, a primary response gene induced by growth factors and tumor promoters.

Authors: B S Fletcher; R W Lim; B C Varnum; D A Kujubu; R A Koski; H R Herschman
Journal: J Biol Chem Date: 1991-08-05 Impact factor: 5.157

3. Solvent content of protein crystals.

Authors: B W Matthews
Journal: J Mol Biol Date: 1968-04-28 Impact factor: 5.469

Review 4. The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?

Authors: F Tirone
Journal: J Cell Physiol Date: 2001-05 Impact factor: 6.384

5. Cloning of the mouse BTG3 gene and definition of a new gene family (the BTG family) involved in the negative control of the cell cycle.

Authors: F Guéhenneux; L Duret; M B Callanan; R Bouhas; S Hayette; C Berthet; C Samarut; R Rimokh; A M Birot; Q Wang; J P Magaud; J P Rouault
Journal: Leukemia Date: 1997-03 Impact factor: 11.528

6. Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases.

Authors: N Ikematsu; Y Yoshida; J Kawamura-Tsuzuku; M Ohsugi; M Onda; M Hirai; J Fujimoto; T Yamamoto
Journal: Oncogene Date: 1999-12-09 Impact factor: 9.867

7. Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1.

Authors: J A Bogdan; C Adams-Burton; D L Pedicord; D A Sukovich; P A Benfield; M H Corjay; J K Stoltenborg; I B Dicker
Journal: Biochem J Date: 1998-12-01 Impact factor: 3.857

8. Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.

Authors: Nader Ezzeddine; Tsung-Cheng Chang; Wenmiao Zhu; Akio Yamashita; Chyi-Ying A Chen; Zhenping Zhong; Yukiko Yamashita; Dinghai Zheng; Ann-Bin Shyu
Journal: Mol Cell Biol Date: 2007-09-04 Impact factor: 4.272

9. ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system.

Authors: Y Yoshida; S Matsuda; N Ikematsu; J Kawamura-Tsuzuku; J Inazawa; H Umemori; T Yamamoto
Journal: Oncogene Date: 1998-05 Impact factor: 9.867