Literature DB >> 18079986

Synthesis of irreversibly binding bicalutamide analogs for imaging studies.

Vipin A Nair1, Suni M Mustafa, Michael L Mohler, Jun Yang, Leonid I Kirkovsky, James T Dalton, Duane D Miller.   

Abstract

A new synthetic methodology for preparing radioactive androgen receptor binding compounds in order to determine receptor-ligands interactions has been developed.

Entities:  

Year:  2005        PMID： 18079986      PMCID： PMC2134918          DOI： 10.1016/j.tetlet.2005.04.143

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  14 in total

1.  Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands.

Authors:  C A Marhefka; B M Moore; T C Bishop; L Kirkovsky; A Mukherjee; J T Dalton; D D Miller
Journal:  J Med Chem       Date:  2001-05-24       Impact factor: 7.446

Review 2.  Intracellular receptors and signal transducers and activators of transcription superfamilies: novel targets for small-molecule drug discovery.

Authors:  J Rosen; A Day; T K Jones; E T Jones; A M Nadzan; R B Stein
Journal:  J Med Chem       Date:  1995-12-08       Impact factor: 7.446

3.  Design, synthesis, and pharmacological characterization of 4-[4, 4-dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl]- 2-iodobenzonitrile as a high-affinity nonsteroidal androgen receptor ligand.

Authors:  M E Van Dort; D M Robins; B Wayburn
Journal:  J Med Chem       Date:  2000-08-24       Impact factor: 7.446

4.  Affinity labeling of the androgen receptor with nonsteroidal chemoaffinity ligands.

Authors:  A Mukherjee; L I Kirkovsky; Y Kimura; M M Marvel; D D Miller; J T Dalton
Journal:  Biochem Pharmacol       Date:  1999-10-15       Impact factor: 5.858

5.  Chiral nonsteroidal affinity ligands for the androgen receptor. 1. Bicalutamide analogues bearing electrophilic groups in the B aromatic ring.

Authors:  L Kirkovsky; A Mukherjee; D Yin; J T Dalton; D D Miller
Journal:  J Med Chem       Date:  2000-02-24       Impact factor: 7.446

6.  Pharmacodynamics of selective androgen receptor modulators.

Authors:  Donghua Yin; Wenqing Gao; Jeffrey D Kearbey; Huiping Xu; Kiwon Chung; Yali He; Craig A Marhefka; Karen A Veverka; Duane D Miller; James T Dalton
Journal:  J Pharmacol Exp Ther       Date:  2003-03       Impact factor: 4.030

7.  A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor.

Authors:  Casey E Bohl; Cheng Chang; Michael L Mohler; Jiyun Chen; Duane D Miller; Peter W Swaan; James T Dalton
Journal:  J Med Chem       Date:  2004-07-15       Impact factor: 7.446

Review 8.  Toxicity of tin and its compounds.

Authors:  K A Winship
Journal:  Adverse Drug React Acute Poisoning Rev       Date:  1988

9.  Non-steroidal antiandrogens. Design of novel compounds based on an infrared study of the dominant conformation and hydrogen-bonding properties of a series of anilide antiandrogens.

Authors:  J J Morris; L R Hughes; A T Glen; P J Taylor
Journal:  J Med Chem       Date:  1991-01       Impact factor: 7.446

Review 10.  The steroid and thyroid hormone receptor superfamily.

Authors:  R M Evans
Journal:  Science       Date:  1988-05-13       Impact factor: 47.728
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  3 in total

1.  Synthesis of oxazolidinedione derived bicalutamide analogs.

Authors:  Vipin A Nair; Suni M Mustafa; Michael L Mohler; James T Dalton; Duane D Miller
Journal:  Tetrahedron Lett       Date:  2006-06-05       Impact factor: 2.415

2.  Asymmetric synthesis of host-directed inhibitors of myxoviruses.

Authors:  Terry W Moore; Kasinath Sana; Dan Yan; Pahk Thepchatri; John M Ndungu; Manohar T Saindane; Mark A Lockwood; Michael G Natchus; Dennis C Liotta; Richard K Plemper; James P Snyder; Aiming Sun
Journal:  Beilstein J Org Chem       Date:  2013-01-30       Impact factor: 2.883

3.  Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery.

Authors:  Jeroen B I Sap; Natan J W Straathof; Thomas Knauber; Claudio F Meyer; Maurice Médebielle; Laura Buglioni; Christophe Genicot; Andrés A Trabanco; Timothy Noël; Christopher W Am Ende; Véronique Gouverneur
Journal:  J Am Chem Soc       Date:  2020-05-11       Impact factor: 15.419
  3 in total

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