Literature DB >> 18078037

[Therapeutic effect of p-tyrosol on myocardial electric instability induced by coronary occlusion].

G A Chernyshov, M B Plotnikov, V I Smol'iakova, E A Krasnov.   

Abstract

In experiments on rats with left coronary artery occlusion, p-tyrosol (20 mg/kg, intravenously) showed the ability to decrease myocardial electric instability in phase 1b of ventricular arrhythmias: a fraction of rats without arrhythmia was increased by 36%, and the mean value of ventricular arrhythmia index exhibited a 3-fold decrease.

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Year:  2007        PMID: 18078037

Source DB:  PubMed          Journal:  Eksp Klin Farmakol        ISSN: 0869-2092


  2 in total

1.  A rapid determination of drug candidate tyrosol galactoside in rat plasma by HPLC and its application to the pharmacokinetics study.

Authors:  Qingwei Wang; Yu Wang; Yating Deng; Tianrao Shi; Xueying Liu; Xiaoli Sun; Xiaoye Li; Dan Zhou
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2010-10-14       Impact factor: 2.441

2.  Beneficial effects of tyrosol on altered glycoprotein components in streptozotocin-induced diabetic rats.

Authors:  Ramasamy Chandramohan; Settu Saravanan; Leelavinothan Pari
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

  2 in total

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