OBJECTIVE: To compare polysomnography (PSG) and self-reported sleep, symptoms (pain and fatigue), and anxiety between children with active and inactive juvenile rheumatoid arthritis (JRA) and examine relations among sleep, symptoms, and anxiety. METHODS: Two consecutive nights of PSG, self-reported sleep, and symptoms were obtained in 70 children 6-11 years of age with active (n = 35) or inactive (n = 35) JRA. RESULTS: On the second (study) night, PSG and self-reported sleep variables were not different, but pain and fatigue were significantly higher (both p <.02) in children with active compared to inactive disease. In a stepwise regression, age, medications, disease status, anxiety, evening pain, total sleep time, and arousals explained 36% of the variance in fatigue and age, disease status, and evening pain were significant (all p <.04) predictors of fatigue. All children showed longer sleep latency and reduced sleep efficiency on the first night in the laboratory. CONCLUSIONS: Sleep was not altered in children with active JRA, however, the "first night effect" suggests that valid laboratory sleep assessments require an adaptation night.
OBJECTIVE: To compare polysomnography (PSG) and self-reported sleep, symptoms (pain and fatigue), and anxiety between children with active and inactive juvenile rheumatoid arthritis (JRA) and examine relations among sleep, symptoms, and anxiety. METHODS: Two consecutive nights of PSG, self-reported sleep, and symptoms were obtained in 70 children 6-11 years of age with active (n = 35) or inactive (n = 35) JRA. RESULTS: On the second (study) night, PSG and self-reported sleep variables were not different, but pain and fatigue were significantly higher (both p <.02) in children with active compared to inactive disease. In a stepwise regression, age, medications, disease status, anxiety, evening pain, total sleep time, and arousals explained 36% of the variance in fatigue and age, disease status, and evening pain were significant (all p <.04) predictors of fatigue. All children showed longer sleep latency and reduced sleep efficiency on the first night in the laboratory. CONCLUSIONS: Sleep was not altered in children with active JRA, however, the "first night effect" suggests that valid laboratory sleep assessments require an adaptation night.
Authors: Maria-Eleni Roumelioti; Alicia Wentz; Michael F Schneider; Arlene C Gerson; Stephen Hooper; Mark Benfield; Bradley A Warady; Susan L Furth; Mark L Unruh Journal: Am J Kidney Dis Date: 2010-01-19 Impact factor: 8.860
Authors: Teresa M Ward; Maida Lynn Chen; Carol A Landis; Sarah Ringold; Dean W Beebe; Kenneth C Pike; Carol A Wallace Journal: Qual Life Res Date: 2016-12-16 Impact factor: 4.147
Authors: Teresa M Ward; Kristen Archbold; Martha Lentz; Sarah Ringold; Carol A Wallace; Carol A Landis Journal: Sleep Date: 2010-02 Impact factor: 5.849
Authors: Teresa M Ward; Sarah Ringold; Jonika Metz; Kristen Archbold; Martha Lentz; Carol A Wallace; Carol A Landis Journal: Arthritis Care Res (Hoboken) Date: 2011-07 Impact factor: 4.794