| Literature DB >> 18073230 |
Joanna Deperas1, Marta Szluinska, Marta Deperas-Kaminska, Alan Edwards, David Lloyd, Carita Lindholm, Horst Romm, Laurence Roy, Raymond Moss, Josselin Morand, Andrzej Wojcik.
Abstract
The aim of biological dosimetry is to estimate the dose and the associated uncertainty to which an accident victim was exposed. This process requires the use of the maximum-likelihood method for fitting a calibration curve, a procedure that is not implemented in most statistical computer programs. Several laboratories have produced their own programs, but these are frequently not user-friendly and not available to outside users. We developed a software for fitting a linear-quadratic dose-response relationship by the method of maximum-likelihood and for estimating a dose from the number of aberrations observed. The program called as CABAS consists of the main curve-fitting and dose estimating module and modules for calculating the dose in cases of partial body exposure, for estimating the minimum number of cells necessary to detect a given dose of radiation and for calculating the dose in the case of a protracted exposure. The program is freely available at http://www.pu.kielce.pl/ibiol/cabas.Mesh：
Year: 2007 PMID： 18073230 DOI： 10.1093/rpd/ncm137
Source DB: PubMed Journal: Radiat Prot Dosimetry ISSN： 0144-8420 Impact factor: 0.972