Literature DB >> 18069748

Coupling desorption electrospray ionisation and neutral desorption/extractive electrospray ionisation with a travelling-wave based ion mobility mass spectrometer for the analysis of drugs.

Jonathan P Williams1, James H Scrivens.   

Abstract

Desorption electrospray ionisation (DESI) and neutral desorption/extractive electrospray ionisation (EESI) have been coupled to a hybrid quadrupole travelling-wave (T-Wave)-based ion mobility time-of-flight mass spectrometer for the direct accurate mass analysis of active ingredients formulated into pharmaceutical samples. The collision cross-section measurements of polyethylene glycol (PEG) excipients detected in one formulation were estimated and compared with published data. These estimated collision cross-sections of the PEG species showed good agreement with published data. Copyright (c) 2007 John Wiley & Sons, Ltd.

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Year:  2008        PMID: 18069748     DOI: 10.1002/rcm.3346

Source DB:  PubMed          Journal:  Rapid Commun Mass Spectrom        ISSN: 0951-4198            Impact factor:   2.419


  19 in total

1.  Protein Structural Studies by Traveling Wave Ion Mobility Spectrometry: A Critical Look at Electrospray Sources and Calibration Issues.

Authors:  Yu Sun; Siavash Vahidi; Modupeola A Sowole; Lars Konermann
Journal:  J Am Soc Mass Spectrom       Date:  2015-09-14       Impact factor: 3.109

2.  Preparation, separation, and conformational analysis of differentially sulfated heparin octasaccharide isomers using ion mobility mass spectrometry.

Authors:  Youjin Seo; Armann Andaya; Julie A Leary
Journal:  Anal Chem       Date:  2012-02-14       Impact factor: 6.986

3.  Neutral desorption using a sealed enclosure to sample explosives on human skin for rapid detection by EESI-MS.

Authors:  Huanwen Chen; Bin Hu; Yan Hu; Yanfu Huan; Zhiquan Zhou; Xiaolin Qiao
Journal:  J Am Soc Mass Spectrom       Date:  2008-12-27       Impact factor: 3.109

Review 4.  What can we learn from ambient ionization techniques?

Authors:  Huanwen Chen; Gerardo Gamez; Renato Zenobi
Journal:  J Am Soc Mass Spectrom       Date:  2009-08-13       Impact factor: 3.109

5.  On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry.

Authors:  Jonathan Stauber; Luke MacAleese; Julien Franck; Emmanuelle Claude; Marten Snel; Basak Kükrer Kaletas; Ingrid M V D Wiel; Maxence Wisztorski; Isabelle Fournier; Ron M A Heeren
Journal:  J Am Soc Mass Spectrom       Date:  2009-09-29       Impact factor: 3.109

6.  Shape changes induced by N-terminal platination of ubiquitin by cisplatin.

Authors:  Jonathan P Williams; Hazel I A Phillips; Iain Campuzano; Peter J Sadler
Journal:  J Am Soc Mass Spectrom       Date:  2010-02-11       Impact factor: 3.109

Review 7.  Size, weight and position: ion mobility spectrometry and imaging MS combined.

Authors:  András Kiss; Ron M A Heeren
Journal:  Anal Bioanal Chem       Date:  2011-01-13       Impact factor: 4.142

8.  Biologically Relevant Metal-Cation Binding Induces Conformational Changes in Heparin Oligosaccharides as Measured by Ion Mobility Mass Spectrometry.

Authors:  Youjin Seo; Matthew R Schenauer; Julie A Leary
Journal:  Int J Mass Spectrom       Date:  2011-06-01       Impact factor: 1.986

9.  Isomer separation and gas-phase configurations of organoruthenium anticancer complexes: ion mobility mass spectrometry and modeling.

Authors:  Jonathan P Williams; Tijana Bugarcic; Abraha Habtemariam; Kevin Giles; Iain Campuzano; P Mark Rodger; Peter J Sadler
Journal:  J Am Soc Mass Spectrom       Date:  2009-02-14       Impact factor: 3.109

10.  Artificial neural networks for the prediction of peptide drift time in ion mobility mass spectrometry.

Authors:  Bing Wang; Steve Valentine; Manolo Plasencia; Sriram Raghuraman; Xiang Zhang
Journal:  BMC Bioinformatics       Date:  2010-04-11       Impact factor: 3.169

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