Literature DB >> 18066514

[Primary malignant melanoma of the parotid gland: a case report and review of the literature].

H Maier1, G Mühlmeier, K Kraft, N M Blumstein, M Tisch.   

Abstract

Malignant melanomas (MMs) of the parotid gland are relatively uncommon. They occur almost invariably as metastases from a primary tumour located in the region of the scalp or the mucous membranes of the nose, paranasal sinuses, or throat. Primary MMs arising in the parotid gland are extremely rare. It is assumed that they originate in the glandular tissue or in intraglandular lymph nodes. We present a case report and review of the literature on the diagnosis, treatment, and prognosis of intraparotid malignant melanoma. Diagnosis is based primarily on B-scan ultrasonography and fine-needle aspiration cytology. Patients with a cytological diagnosis of MM are further evaluated by magnetic resonance imaging and positron emission tomography and receive a thorough ear-nose-throat and dermatological examination. The treatment of choice is total parotidectomy and selective neck dissection. The effectiveness of adjuvant treatments such as radiotherapy, chemotherapy, or immunotherapy remains controversial. Patients with primary MMs of the parotid gland appear to have a better prognosis than those with parotid metastases from melanomas of the skin or mucous membranes.

Entities:  

Mesh:

Year:  2008        PMID: 18066514     DOI: 10.1007/s00106-007-1634-5

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  27 in total

1.  MRI and malignant melanoma of the parotid gland.

Authors:  Y Ismail; N R McLean; A J Chippindale
Journal:  Br J Plast Surg       Date:  2001-10

2.  MALIGNANT MELANOMA OF UNKNOWN PRIMARY ORIGIN.

Authors:  T DASGUPTA; L BOWDEN; J W BERG
Journal:  Surg Gynecol Obstet       Date:  1963-09

3.  Adjuvant radiotherapy following neck dissection and parotidectomy for metastatic malignant melanoma.

Authors:  C J O'Brien; K Petersen-Schaefer; G N Stevens; P C Bass; P Tew; V J Gebski; J F Thompson; W H McCarthy
Journal:  Head Neck       Date:  1997-10       Impact factor: 3.147

Review 4.  Spontaneous regression of metastatic malignant melanoma of the parotid gland and neck lymph nodes: a case report and a review of the literature.

Authors:  M King; D Spooner; D C Rowlands
Journal:  Clin Oncol (R Coll Radiol)       Date:  2001       Impact factor: 4.126

Review 5.  [Can preoperative fine-needle aspiration of parotid tumors pose problems for a definitive histological diagnosis?].

Authors:  H Maier; S Frühwald; S Sommer; M Tisch
Journal:  HNO       Date:  2006-03       Impact factor: 1.284

6.  Complete regression of primary cutaneous malignant melanoma.

Authors:  S W Menzies; W H McCarthy
Journal:  Arch Surg       Date:  1997-05

7.  Melanoma metastatic to cervical and parotid nodes from an unknown primary site.

Authors:  H Santini; R M Byers; P F Wolf
Journal:  Am J Surg       Date:  1985-10       Impact factor: 2.565

8.  [Melanoma metastasis in the neck region with unknown primary tumor].

Authors:  H J Schultz-Coulon; H H Peter
Journal:  Laryngol Rhinol Otol (Stuttg)       Date:  1984-01

9.  Malignant melanoma of cervical and parotid lymph nodes with an unknown primary site.

Authors:  S Nasri; A Namazie; P Dulguerov; R Mickel
Journal:  Laryngoscope       Date:  1994-10       Impact factor: 3.325

10.  Lymph node metastases in the neck and parotid gland from an unknown primary melanoma.

Authors:  A J Balm; B B Kroon; F J Hilgers; A Jonk; W J Mooi
Journal:  Clin Otolaryngol Allied Sci       Date:  1994-04
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