Literature DB >> 18058881

Asymmetric synthesis and biological properties of uncialamycin and 26-epi-uncialamycin.

K C Nicolaou1, Jason S Chen, Hongjun Zhang, Ana Montero.   

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Year:  2008        PMID： 18058881     DOI： 10.1002/anie.200704577

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  10 in total

Review 1.  Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors:  K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal:  Chem Soc Rev       Date:  2012-06-28       Impact factor: 54.564

2.  Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne.

Authors:  Xiaohui Yan; Jian-Jun Chen; Ajeeth Adhikari; Dong Yang; Ivana Crnovcic; Nan Wang; Chin-Yuan Chang; Christoph Rader; Ben Shen
Journal:  Org Lett       Date:  2017-10-31       Impact factor: 6.005

3.  Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis.

Authors:  Xiaohui Yan; Jian-Jun Chen; Ajeeth Adhikari; Christiana N Teijaro; Huiming Ge; Ivana Crnovcic; Chin-Yuan Chang; Thibault Annaval; Dong Yang; Christoph Rader; Ben Shen
Journal:  Org Lett       Date:  2018-09-13       Impact factor: 6.005

Review 4.  Organic synthesis: the art and science of replicating the molecules of living nature and creating others like them in the laboratory.

Authors:  K C Nicolaou
Journal:  Proc Math Phys Eng Sci       Date:  2014-03-08       Impact factor: 2.704

5.  Perspectives from nearly five decades of total synthesis of natural products and their analogues for biology and medicine.

Authors:  K C Nicolaou; Stephan Rigol
Journal:  Nat Prod Rep       Date:  2020-04-22       Impact factor: 13.423

6.  Oxone promoted dehydrogenative Povarov cyclization of N-aryl glycine derivatives: an approach towards quinoline fused lactones and lactams.

Authors:  Devidas A More; Ganesh H Shinde; Aslam C Shaikh; M Muthukrishnan
Journal:  RSC Adv       Date:  2019-09-25       Impact factor: 4.036

7.  Inspirations, discoveries, and future perspectives in total synthesis.

Authors:  K C Nicolaou
Journal:  J Org Chem       Date:  2009-02-06       Impact factor: 4.354

8.  Characterization of TnmH as an O-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates.

Authors:  Ajeeth Adhikari; Christiana N Teijaro; Xiaohui Yan; Chin-Yuan Chang; Chun Gui; Yu-Chen Liu; Ivana Crnovcic; Dong Yang; Thibault Annaval; Christoph Rader; Ben Shen
Journal:  J Med Chem       Date:  2020-07-24       Impact factor: 7.446

9.  From nature to the laboratory and into the clinic.

Authors:  K C Nicolaou; Jason S Chen; Stephen M Dalby
Journal:  Bioorg Med Chem       Date:  2008-11-06       Impact factor: 3.641

10.  Uncialamycin-based antibody-drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect.

Authors:  K C Nicolaou; Stephan Rigol; Emmanuel N Pitsinos; Dipendu Das; Yong Lu; Subhrajit Rout; Alexander W Schammel; Dane Holte; Baiwei Lin; Christine Gu; Hetal Sarvaiya; Jose Trinidad; Nicole Barbour; Amanda M Valdiosera; Joseph Sandoval; Christina Lee; Monette Aujay; Hanan Fernando; Anukriti Dhar; Holger Karsunky; Nicole Taylor; Marybeth Pysz; Julia Gavrilyuk
Journal:  Proc Natl Acad Sci U S A       Date:  2021-06-22       Impact factor: 11.205
  10 in total

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