Literature DB >> 18054270

Investigating oxidative DNA damage and its repair using the comet assay.

Andrew R Collins1.   

Abstract

The comet assay is not the only way to measure oxidative DNA damage, but it is one of the most sensitive and accurate, being relatively free of artefacts. It is a valuable tool in population monitoring, for example in assessing the role of oxidative stress in human disease, and in monitoring the effects of dietary antioxidants. A simple modification allows the measurement of DNA repair. In combination with the analysis of polymorphisms in relevant genes, the comet assay - especially when adapted for analysis of large numbers of samples - can provide important information on the interactions between genetic variation and environmental factors in maintaining genome stability.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 18054270     DOI： 10.1016/j.mrrev.2007.10.002

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  51 in total

1.  High molecular weight hyaluronan decreases oxidative DNA damage induced by EDTA in human corneal epithelial cells.

Authors:  J Ye; H Wu; Y Wu; C Wang; H Zhang; X Shi; J Yang
Journal:  Eye (Lond)       Date:  2012-05-18       Impact factor: 3.775

2.  DNA damage phenotype and prostate cancer risk.

Authors:  O Kosti; L Goldman; D T Saha; R A Orden; A J Pollock; H L Madej; A W Hsing; L W Chu; J H Lynch; R Goldman
Journal:  Mutat Res       Date:  2010-11-21       Impact factor: 2.433

3.  In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver.

Authors:  Wei Ding; Michelle E Bishop; Lascelles E Lyn-Cook; Kelly J Davis; Mugimane G Manjanatha
Journal:  J Vis Exp       Date:  2016-05-04       Impact factor: 1.355

4.  The use of antioxidative stress enzymes, lipid peroxidation, and red blood cell abnormalities as biomarkers of stress in Periphthalmus papilio of the polluted coastal Lagos lagoon.

Authors:  Amaeze H Nnamdi; Adebesin A Olumide; Adepegba E Adeladun; Kolapo Oyenike; Egonmwan I Rosemary
Journal:  Environ Monit Assess       Date:  2015-02-10       Impact factor: 2.513

5.  Quercitrin protects skin from UVB-induced oxidative damage.

Authors:  Yuanqin Yin; Wenqi Li; Young-Ok Son; Lijuan Sun; Jian Lu; Donghern Kim; Xin Wang; Hua Yao; Lei Wang; Poyil Pratheeshkumar; Andrew J Hitron; Jia Luo; Ning Gao; Xianglin Shi; Zhuo Zhang
Journal:  Toxicol Appl Pharmacol       Date:  2013-03-29       Impact factor: 4.219

6.  Toxicity assessment of the water used for human consumption from the Cameron/Tuba City abandoned uranium mining area prior/after the combined electrochemical treatment/advanced oxidation.

Authors:  Goran Gajski; Višnja Oreščanin; Marko Gerić; Robert Kollar; Ivanka Lovrenčić Mikelić; Vera Garaj-Vrhovac
Journal:  Environ Sci Pollut Res Int       Date:  2014-08-05       Impact factor: 4.223

7.  Bioaccumulation of butyltins and liver damage in the demersal fish Cathorops spixii (Siluriformes, Ariidae).

Authors:  Dayana Moscardi Dos Santos; Gustavo Souza Santos; Marta Margarete Cestari; Ciro Alberto de Oliveira Ribeiro; Helena Cristina Silva de Assis; Flavia Yamamoto; Izonete Cristina Guiloski; Mary Rosa Rodrigues de Marchi; Rosalinda Carmela Montone
Journal:  Environ Sci Pollut Res Int       Date:  2013-11-12       Impact factor: 4.223

8.  Gene polymorphisms against DNA damage induced by hydrogen peroxide in leukocytes of healthy humans through comet assay: a quasi-experimental study.

Authors:  Ana L Miranda-Vilela; Penha Cz Alves; Arthur K Akimoto; Graciana S Lordelo; Carlos A Gonçalves; Cesar K Grisolia; Maria N Klautau-Guimarães
Journal:  Environ Health       Date:  2010-05-05       Impact factor: 5.984

9.  Introducing a true internal standard for the Comet assay to minimize intra- and inter-experiment variability in measures of DNA damage and repair.

Authors:  Murizal Zainol; Julia Stoute; Gabriela M Almeida; Alexander Rapp; Karen J Bowman; George D D Jones
Journal:  Nucleic Acids Res       Date:  2009-12       Impact factor: 16.971

10.  DNA damage/repair and polymorphism of the hOGG1 gene in lymphocytes of AMD patients.

Authors:  Katarzyna Wozniak; Jacek P Szaflik; Malgorzata Zaras; Anna Sklodowska; Katarzyna Janik-Papis; Tomasz R Poplawski; Janusz Blasiak; Jerzy Szaflik
Journal:  J Biomed Biotechnol       Date:  2009-10-26
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.