| Literature DB >> 18054234 |
Maria Zannis-Hadjopoulos1, Wafaa Yahyaoui, Mario Callejo.
Abstract
Cruciforms are secondary DNA structures, serving as recognition signals at or near eukaryotic (yeast and mammalian) origins of DNA replication. The cruciform-binding protein is a member of the 14-3-3 protein family and binds to origins of DNA replication in a cell cycle-dependent manner. Five 14-3-3 protein isoforms (beta, gamma, epsilon, zeta and sigma) have been identified as having cruciform binding activity.Entities:
Mesh:
Substances:
Year: 2007 PMID: 18054234 DOI: 10.1016/j.tibs.2007.09.012
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807