OBJECTIVE: To describe patients who reported treatment-induced infertility 2 years after cancer diagnosis and to highlight what factors are related to the patients' lack of information on this topic before starting therapy. DESIGN: Cross-sectional study by telephone interview. SETTING: Representative French national sample of survivors 2 years after cancer diagnosis. PATIENT(S): 282 women (<45 years) and 1137 men (<71 years). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Self-reported treatment-induced infertility, and what information was provided on this issue before starting treatment, including information on systematic sperm cryopreservation. RESULT(S): Among the participants, 104 women (37%) and 346 men (30%) reported having treatment-induced infertility. Among them, 31 women (30%) and 45 men (13%) reported that they had not been informed about the risk of infertility before they started treatment. Logistic regressions showed that a lack of information was associated with older age and treatment without hormone therapy among women and older age, cancers other than prostate, and a lack of participation in treatment decision-making among men. CONCLUSION(S): Information about infertility risks and preservation methods should be provided more systematically to all treated patients, irrespective of their age.
OBJECTIVE: To describe patients who reported treatment-induced infertility 2 years after cancer diagnosis and to highlight what factors are related to the patients' lack of information on this topic before starting therapy. DESIGN: Cross-sectional study by telephone interview. SETTING: Representative French national sample of survivors 2 years after cancer diagnosis. PATIENT(S): 282 women (<45 years) and 1137 men (<71 years). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Self-reported treatment-induced infertility, and what information was provided on this issue before starting treatment, including information on systematic sperm cryopreservation. RESULT(S): Among the participants, 104 women (37%) and 346 men (30%) reported having treatment-induced infertility. Among them, 31 women (30%) and 45 men (13%) reported that they had not been informed about the risk of infertility before they started treatment. Logistic regressions showed that a lack of information was associated with older age and treatment without hormone therapy among women and older age, cancers other than prostate, and a lack of participation in treatment decision-making among men. CONCLUSION(S): Information about infertility risks and preservation methods should be provided more systematically to all treated patients, irrespective of their age.
Authors: D Howell; T F Hack; T K Oliver; T Chulak; S Mayo; M Aubin; M Chasen; C C Earle; A J Friedman; E Green; G W Jones; J M Jones; M Parkinson; N Payeur; C M Sabiston; S Sinclair Journal: J Cancer Surviv Date: 2012-07-10 Impact factor: 4.442
Authors: Joseph M Letourneau; James F Smith; Erin E Ebbel; Amaranta Craig; Patricia P Katz; Marcelle I Cedars; Mitchell P Rosen Journal: Cancer Date: 2012-03-26 Impact factor: 6.860