Literature DB >> 18043873

Recent applications of Kirkwood-Buff theory to biological systems.

Veronica Pierce1, Myungshim Kang, Mahalaxmi Aburi, Samantha Weerasinghe, Paul E Smith.   

Abstract

The effect of cosolvents on biomolecular equilibria has traditionally been rationalized using simple binding models. More recently, a renewed interest in the use of Kirkwood-Buff (KB) theory to analyze solution mixtures has provided new information on the effects of osmolytes and denaturants and their interactions with biomolecules. Here we review the status of KB theory as applied to biological systems. In particular, the existing models of denaturation are analyzed in terms of KB theory, and the use of KB theory to interpret computer simulation data for these systems is discussed.

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Year:  2007        PMID: 18043873      PMCID: PMC2566781          DOI: 10.1007/s12013-007-9005-0

Source DB:  PubMed          Journal:  Cell Biochem Biophys        ISSN: 1085-9195            Impact factor:   2.194


  101 in total

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  33 in total

1.  A Kirkwood-Buff force field for the aromatic amino acids.

Authors:  Elizabeth A Ploetz; Paul E Smith
Journal:  Phys Chem Chem Phys       Date:  2011-09-19       Impact factor: 3.676

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Authors:  Elizabeth A Ploetz; Nikolaos Bentenitis; Paul E Smith
Journal:  J Chem Phys       Date:  2010-04-28       Impact factor: 3.488

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Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-12       Impact factor: 11.205

4.  Local Fluctuations in Solution: Theory and Applications.

Authors:  Elizabeth A Ploetz; Paul E Smith
Journal:  Adv Chem Phys       Date:  2013       Impact factor: 1.000

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Authors:  Myungshim Kang; Paul E Smith
Journal:  J Chem Phys       Date:  2008-06-28       Impact factor: 3.488

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