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Literature DB >> 18040828

Biomarkers for neuroAIDS: the widening scope of metabolomics.

Gurudutt Pendyala¹, Elizabeth J Want, William Webb, Gary Siuzdak, Howard S Fox.

Abstract

"Metabolomics", the measurement of metabolite concentrations and fluxes in cell systems, is an emerging science that has enormous potential and several unique characteristics. The current applications for this field are, primarily, toxicological profiling and biomarker studies. This review of metabolomics research highlights the identification of reliable biomarkers with emphasis on neuroAIDS. Such identification of candidate markers will be advantageous for tracking the progression of human immunodeficiency virus/central nervous system (HIV/CNS) disease to gain maximal benefit from antiretroviral treatment and to provide insight into the mechanism of related neuropathogenesis.

Entities: Disease

Mesh：

Substances：
Biomarkers

Year: 2006 PMID： 18040828 DOI： 10.1007/s11481-006-9041-3

Source DB: PubMed Journal: J Neuroimmune Pharmacol ISSN： 1557-1890 Impact factor: 4.147

74 in total

Review 1. Metabonomics: a platform for studying drug toxicity and gene function.

Authors: Jeremy K Nicholson; John Connelly; John C Lindon; Elaine Holmes
Journal: Nat Rev Drug Discov Date: 2002-02 Impact factor: 84.694

Review 2. The application of NMR-based metabonomics in neurological disorders.

Authors: Elaine Holmes; Tsz M Tsang; Sarah J Tabrizi
Journal: NeuroRx Date: 2006-07

Review 3. Pathology of HIV-1 infection of the central nervous system. A review.

Authors: L R Sharer
Journal: J Neuropathol Exp Neurol Date: 1992-01 Impact factor: 3.685

Review 4. Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system.

Authors: K Williams; X Alvarez; A A Lackner
Journal: Glia Date: 2001-11 Impact factor: 7.452

5. Combined HPLC-MS and HPLC-NMR on-line coupling for the separation and determination of lutein and zeaxanthin stereoisomers in spinach and in retina.

Authors: M Dachtler; T Glaser; K Kohler; K Albert
Journal: Anal Chem Date: 2001-02-01 Impact factor: 6.986

Review 6. Simian immunodeficiency virus: a model for neuroAIDS.

Authors: H S Fox; L H Gold; S J Henriksen; F E Bloom
Journal: Neurobiol Dis Date: 1997 Impact factor: 5.996

7. Induction of pathogenic sets of genes in macrophages and neurons in NeuroAIDS.

Authors: Eleanor S Roberts; Michelle A Zandonatti; Debbie D Watry; Lisa J Madden; Steven J Henriksen; Michael A Taffe; Howard S Fox
Journal: Am J Pathol Date: 2003-06 Impact factor: 4.307

8. Early viral brain invasion in iatrogenic human immunodeficiency virus infection.

Authors: L E Davis; B L Hjelle; V E Miller; D L Palmer; A L Llewellyn; T L Merlin; S A Young; R G Mills; W Wachsman; C A Wiley
Journal: Neurology Date: 1992-09 Impact factor: 9.910

9. Global protein identification and quantification technology using two-dimensional liquid chromatography nanospray mass spectrometry.

Authors: Dirk Chelius; Terry Zhang; Guanghui Wang; Rong-Fong Shen
Journal: Anal Chem Date: 2003-12-01 Impact factor: 6.986

Review 10. Measuring the metabolome: current analytical technologies.

Authors: Warwick B Dunn; Nigel J C Bailey; Helen E Johnson
Journal: Analyst Date: 2005-03-04 Impact factor: 4.616

11 in total

1. Metabolomics reveals differential levels of oral metabolites in HIV-infected patients: toward novel diagnostic targets.

Authors: Mahmoud A Ghannoum; Pranab K Mukherjee; Richard J Jurevic; Mauricio Retuerto; Robert E Brown; Masoumeh Sikaroodi; Jennifer Webster-Cyriaque; Patrick M Gillevet
Journal: OMICS Date: 2011-07-13

Review 2. Metabolomics: moving to the clinic.

Authors: Anders Nordström; Rolf Lewensohn
Journal: J Neuroimmune Pharmacol Date: 2009-04-28 Impact factor: 4.147

3. Glutamate metabolism in HIV-1 infected macrophages: Role of HIV-1 Vpr.

Authors: Prasun K Datta; Satish Deshmane; Kamel Khalili; Salim Merali; John C Gordon; Chiara Fecchio; Carlos A Barrero
Journal: Cell Cycle Date: 2016-05-31 Impact factor: 4.534

4. MALDI-mass spectrometric imaging for the investigation of metabolites in Medicago truncatula root nodules.

Authors: Erin Gemperline; Lingjun Li
Journal: J Vis Exp Date: 2014-03-05 Impact factor: 1.355

5. Metabolic Profiling of Human Blood by High Resolution Ion Mobility Mass Spectrometry (IM-MS).

Authors: Prabha Dwivedi; Albert J Schultz; Herbert H Hill
Journal: Int J Mass Spectrom Date: 2010-12 Impact factor: 1.986

6. Proteomic and metabolomic strategies to investigate HIV-associated neurocognitive disorders.

Authors: Gurudutt Pendyala; Howard S Fox
Journal: Genome Med Date: 2010-03-30 Impact factor: 11.117

7. Animal models of virus-induced neurobehavioral sequelae: recent advances, methodological issues, and future prospects.

Authors: Marco Bortolato; Sean C Godar
Journal: Interdiscip Perspect Infect Dis Date: 2010-05-18

8. Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders.

Authors: Jerel Fields; Wilmar Dumaop; Anthony Adame; Ronald J Ellis; Scott Letendre; Igor Grant; Eliezer Masliah
Journal: J Neuroimmune Pharmacol Date: 2013-11-30 Impact factor: 4.147

9. Impact of Tobacco Smoke in HIV Progression: a Major Risk Factor for the Development of NeuroAIDS and Associated of CNS Disorders.

Authors: Aditya Bhalerao; Luca Cucullo
Journal: Z Gesundh Wiss Date: 2019-03-09

Review 10. Disturbed Amino Acid Metabolism in HIV: Association with Neuropsychiatric Symptoms.

Authors: Johanna M Gostner; Kathrin Becker; Katharina Kurz; Dietmar Fuchs
Journal: Front Psychiatry Date: 2015-07-14 Impact factor: 4.157