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Literature DB >> 1803998

Correlation between aminoglycoside resistance profiles and DNA hybridization of clinical isolates.

K J Shaw¹, R S Hare, F J Sabatelli, M Rizzo, C A Cramer, L Naples, S Kocsi, H Munayyer, P Mann, G H Miller.

Abstract

DNA hybridization data and aminoglycoside resistance profiles (AGRPs) were determined for 4,088 clinical isolates from three studies (United States, Belgium, and Argentina). The correlation between susceptibility profiles and hybridization results was determined with nine DNA probes. For each of the seven aminoglycoside resistance profiles which we were able to test, the data suggested at least two distinct genes could encode enzymes which lead to identical resistance profiles. Furthermore, the DNA hybridization data showed that individual strains carried up to six unique aminoglycoside resistance genes. DNA hybridization revealed interesting differences in the frequencies of these genes by organism and by country.

Entities: Chemical

Mesh：

Substances：

Year: 1991 PMID： 1803998 PMCID： PMC245368 DOI： 10.1128/AAC.35.11.2253

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

24 in total

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Journal: Antimicrob Agents Chemother Date: 1987-04 Impact factor: 5.191

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Authors: S Hollingshead; D Vapnek
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Journal: Antimicrob Agents Chemother Date: 1985-05 Impact factor: 5.191

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Journal: Science Date: 1985-10-04 Impact factor: 47.728

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Journal: J Antimicrob Chemother Date: 1987-12 Impact factor: 5.790

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Journal: Antimicrob Agents Chemother Date: 1988-09 Impact factor: 5.191

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Authors: T Lambert; G Gerbaud; P Courvalin
Journal: Antimicrob Agents Chemother Date: 1988-01 Impact factor: 5.191

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Authors: H Ounissi; E Derlot; C Carlier; P Courvalin
Journal: Antimicrob Agents Chemother Date: 1990-11 Impact factor: 5.191

28 in total

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Review 3. Expert systems in clinical microbiology.

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4. Cloning and characterization of an aminoglycoside 6'-N-acetyltransferase gene from Citrobacter freundii which confers an altered resistance profile.

Authors: H Y Wu; G H Miller; M G Blanco; R S Hare; K J Shaw
Journal: Antimicrob Agents Chemother Date: 1997-11 Impact factor: 5.191

Review 5. Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features.

Authors: E Bergogne-Bérézin; K J Towner
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6. Distribution and content of class 1 integrons in different Vibrio cholerae O-serotype strains isolated in Thailand.

Authors: A Dalsgaard; A Forslund; O Serichantalergs; D Sandvang
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7. Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

Authors: J W Chow; V Kak; I You; S J Kao; J Petrin; D B Clewell; S A Lerner; G H Miller; K J Shaw
Journal: Antimicrob Agents Chemother Date: 2001-10 Impact factor: 5.191