BACKGROUND AND PURPOSE: Stroke outcome assessment requires some measure of functional recovery. Several instruments are in common use but all have recognized limitations. We examined duration of stay in the patient's own home over the first 90 days since stroke-"home-time"-as an alternative outcome likely to show graded response with improved reliability. METHODS: We examined prospectively collected data from the GAIN International trial using analysis of variance with Bonferroni contrasts of adjacent modified Rankin scale score categories. RESULTS: We had full outcome data from 1717 of 1788 patients. Increasing home-time was associated with improved modified Rankin scale scores (P<0.0001). The relationship held across all modified Rankin scale grades except 4 to 5. CONCLUSIONS: Home-time offers a robust, useful, and easily validated outcome measure for stroke, particularly across better recovery levels.
BACKGROUND AND PURPOSE:Stroke outcome assessment requires some measure of functional recovery. Several instruments are in common use but all have recognized limitations. We examined duration of stay in the patient's own home over the first 90 days since stroke-"home-time"-as an alternative outcome likely to show graded response with improved reliability. METHODS: We examined prospectively collected data from the GAIN International trial using analysis of variance with Bonferroni contrasts of adjacent modified Rankin scale score categories. RESULTS: We had full outcome data from 1717 of 1788 patients. Increasing home-time was associated with improved modified Rankin scale scores (P<0.0001). The relationship held across all modified Rankin scale grades except 4 to 5. CONCLUSIONS: Home-time offers a robust, useful, and easily validated outcome measure for stroke, particularly across better recovery levels.
Authors: Hormuzdiyar Dasenbrock; William B Gormley; Yoojin Lee; Vincent Mor; Susan L Mitchell; Corey R Fehnel Journal: J Neurosurg Date: 2018-08-17 Impact factor: 5.115
Authors: Amy Y X Yu; Edwin Rogers; Meng Wang; Tolulope T Sajobi; Shelagh B Coutts; Bijoy K Menon; Michael D Hill; Eric E Smith Journal: Neurology Date: 2017-10-11 Impact factor: 9.910
Authors: William J Tate; Laura C Polding; Stephanie Kemp; Michael Mlynash; Jeremy J Heit; Michael P Marks; Gregory W Albers; Maarten G Lansberg Journal: Stroke Date: 2019-07-10 Impact factor: 7.914
Authors: Amgad Mentias; Milind Y Desai; Mary S Vaughan-Sarrazin; Shreya Rao; Alanna A Morris; Jennifer L Hall; Venu Menon; Jason Hockenberry; Mario Sims; Gregg C Fonarow; Saket Girotra; Ambarish Pandey Journal: Circulation Date: 2021-11-08 Impact factor: 39.918
Authors: Matthew F Mart; Timothy D Girard; Jennifer L Thompson; Hannah Whitten-Vile; Rameela Raman; Pratik P Pandharipande; Daren K Heyland; E Wesley Ely; Nathan E Brummel Journal: Clin Nutr Date: 2021-05-11 Impact factor: 7.643
Authors: Tyler R Chesney; Barbara Haas; Natalie G Coburn; Alyson L Mahar; Victoria Zuk; Haoyu Zhao; Frances C Wright; Amy T Hsu; Julie Hallet Journal: JAMA Surg Date: 2020-11-18 Impact factor: 14.766