Literature DB >> 18031037

(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta.

Charles E McKenna1, Boris A Kashemirov, Thomas G Upton, Vinod K Batra, Myron F Goodman, Lars C Pedersen, William A Beard, Samuel H Wilson.   

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Year:  2007        PMID: 18031037      PMCID: PMC2677377          DOI: 10.1021/ja072127v

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


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  22 in total

1.  Comparative study of several algorithms for flexible ligand docking.

Authors:  Badry D Bursulaya; Maxim Totrov; Ruben Abagyan; Charles L Brooks
Journal:  J Comput Aided Mol Des       Date:  2003-11       Impact factor: 3.686

Review 2.  Repair and genetic consequences of endogenous DNA base damage in mammalian cells.

Authors:  Deborah E Barnes; Tomas Lindahl
Journal:  Annu Rev Genet       Date:  2004       Impact factor: 16.830

3.  Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta.

Authors:  Christopher A Sucato; Thomas G Upton; Boris A Kashemirov; Vinod K Batra; Václav Martínek; Yun Xiang; William A Beard; Lars C Pedersen; Samuel H Wilson; Charles E McKenna; Jan Florián; Arieh Warshel; Myron F Goodman
Journal:  Biochemistry       Date:  2007-01-16       Impact factor: 3.162

4.  Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.

Authors:  Chenglong Li; Lan Xu; Dennis W Wolan; Ian A Wilson; Arthur J Olson
Journal:  J Med Chem       Date:  2004-12-30       Impact factor: 7.446

Review 5.  Automated docking of flexible ligands: applications of AutoDock.

Authors:  D S Goodsell; G M Morris; A J Olson
Journal:  J Mol Recognit       Date:  1996 Jan-Feb       Impact factor: 2.137

6.  Effect of triphosphate modifications in 2'-deoxynucleoside 5'-triphosphates on their specificity towards various DNA polymerases.

Authors:  B I Martynov; E A Shirokova; M V Jasko; L S Victorova; A A Krayevsky
Journal:  FEBS Lett       Date:  1997-06-30       Impact factor: 4.124

7.  (Difluoromethylene)phosphates of guanine nucleosides as probes of DNA polymerases and G proteins.

Authors:  L Arabshahi; N N Khan; M Butler; T Noonan; N C Brown; G E Wright
Journal:  Biochemistry       Date:  1990-07-24       Impact factor: 3.162

8.  Purification and domain-mapping of mammalian DNA polymerase beta.

Authors:  W A Beard; S H Wilson
Journal:  Methods Enzymol       Date:  1995       Impact factor: 1.600

9.  2'-Deoxynucleoside 5'-triphosphates modified at alpha-, beta- and gamma-phosphates as substrates for DNA polymerases.

Authors:  L A Alexandrova; A Y Skoblov; M V Jasko; L S Victorova; A A Krayevsky
Journal:  Nucleic Acids Res       Date:  1998-02-01       Impact factor: 16.971

Review 10.  dNTP modified at triphosphate residues: substrate properties towards DNA polymerases and stability in human serum.

Authors:  A Krayevsky; A Arzumanov; E Shirokova; N Dyatkina; L Victorova; M Jasko; L Alexandrova
Journal:  Nucleosides Nucleotides       Date:  1998 Jan-Mar
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  30 in total

1.  Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid.

Authors:  G K Surya Prakash; Mikhail Zibinsky; Thomas G Upton; Boris A Kashemirov; Charles E McKenna; Keriann Oertell; Myron F Goodman; Vinod K Batra; Lars C Pedersen; William A Beard; David D Shock; Samuel H Wilson; George A Olah
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-19       Impact factor: 11.205

2.  Preparation of fluorinated RNA nucleotide analogs potentially stable to enzymatic hydrolysis in RNA and DNA polymerase assays.

Authors:  Anton Shakhmin; John-Paul Jones; Inessa Bychinskaya; Mikhail Zibinsky; Keriann Oertell; Myron F Goodman; G K Surya Prakash
Journal:  J Fluor Chem       Date:  2014-10       Impact factor: 2.050

3.  Stereospecific formation of a ternary complex of (S)-α,β-fluoromethylene-dATP with DNA pol β.

Authors:  Brian T Chamberlain; Vinod K Batra; William A Beard; Anastasia P Kadina; David D Shock; Boris A Kashemirov; Charles E McKenna; Myron F Goodman; Samuel H Wilson
Journal:  Chembiochem       Date:  2012-02-07       Impact factor: 3.164

4.  Probing DNA Base-Dependent Leaving Group Kinetic Effects on the DNA Polymerase Transition State.

Authors:  Keriann Oertell; Boris A Kashemirov; Amirsoheil Negahbani; Corinne Minard; Pouya Haratipour; Khadijeh S Alnajjar; Joann B Sweasy; Vinod K Batra; William A Beard; Samuel H Wilson; Charles E McKenna; Myron F Goodman
Journal:  Biochemistry       Date:  2018-06-19       Impact factor: 3.162

5.  Two Scaffolds from Two Flips: (α,β)/(β,γ) CH2/NH "Met-Im" Analogues of dTTP.

Authors:  Anastasia P Kadina; Boris A Kashemirov; Keriann Oertell; Vinod K Batra; Samuel H Wilson; Myron F Goodman; Charles E McKenna
Journal:  Org Lett       Date:  2015-05-13       Impact factor: 6.005

6.  Kinetic Effects of β,γ-Modified Deoxynucleoside 5'-Triphosphate Analogues on RNA-Catalyzed Polymerization of DNA.

Authors:  Noah A Setterholm; Pouya Haratipour; Boris A Kashemirov; Charles E McKenna; Gerald F Joyce
Journal:  Biochemistry       Date:  2020-12-27       Impact factor: 3.162

7.  A Transition-State Perspective on Y-Family DNA Polymerase η Fidelity in Comparison with X-Family DNA Polymerases λ and β.

Authors:  Keriann Oertell; Jan Florián; Pouya Haratipour; Debbie C Crans; Boris A Kashemirov; Samuel H Wilson; Charles E McKenna; Myron F Goodman
Journal:  Biochemistry       Date:  2019-03-14       Impact factor: 3.162

8.  Synthesis and sensing of bisphosphonophosphate alkyl monoesters: A novel class of compounds for the study of nucleoside 5'-triphosphate chemistry.

Authors:  Brian T Chamberlain; Jorge Osuna; Boris A Kashemirov; Charles E McKenna
Journal:  Phosphorus Sulfur Silicon Relat Elem       Date:  2011-04-01

9.  DNA Polymerase β Cancer-Associated Variant I260M Exhibits Nonspecific Selectivity toward the β-γ Bridging Group of the Incoming dNTP.

Authors:  Khadijeh S Alnajjar; Amirsoheil Negahbani; Maryam Nakhjiri; Ivan S Krylov; Boris A Kashemirov; Charles E McKenna; Myron F Goodman; Joann B Sweasy
Journal:  Biochemistry       Date:  2017-09-20       Impact factor: 3.162

10.  Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT.

Authors:  Fengting Liang; Nidhi Jain; Troy Hutchens; David D Shock; William A Beard; Samuel H Wilson; M Paul Chiarelli; Bongsup P Cho
Journal:  J Med Chem       Date:  2008-09-24       Impact factor: 7.446

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