Michael L Cunningham1, Carrie L Heike. 1. Division of Craniofacial Medicine, University of Washington Department of Pediatrics, Seattle Children's Craniofacial Center, Seattle, Washington 98105, USA. mcunning@u.washington.edu
Abstract
PURPOSE OF REVIEW: Atypical skull shapes occur in as many as 20% of infants. The purpose of this review is to discuss the clinical approach to the evaluation of a child with an abnormal head shape. Readers will learn how to identify the head shapes caused by environmental deformation and craniosynostosis. We also review recent findings with regard to the genetics of single-suture craniosynostosis. RECENT FINDINGS: Healthcare providers can use key aspects of the examination of a child with a head shape abnormality to differentiate positional deformity from craniosynostosis. Overlap between the genetic causes of isolated single-suture craniosynostosis and syndromic forms is discussed. SUMMARY: Pediatricians can identify the causes of the majority of head shape abnormalities by combining their understanding of normal calvarial growth with a careful physical examination. Molecular genetics is playing an increasing role in the evaluation of children with single-suture fusion.
PURPOSE OF REVIEW: Atypical skull shapes occur in as many as 20% of infants. The purpose of this review is to discuss the clinical approach to the evaluation of a child with an abnormal head shape. Readers will learn how to identify the head shapes caused by environmental deformation and craniosynostosis. We also review recent findings with regard to the genetics of single-suture craniosynostosis. RECENT FINDINGS: Healthcare providers can use key aspects of the examination of a child with a head shape abnormality to differentiate positional deformity from craniosynostosis. Overlap between the genetic causes of isolated single-suture craniosynostosis and syndromic forms is discussed. SUMMARY: Pediatricians can identify the causes of the majority of head shape abnormalities by combining their understanding of normal calvarial growth with a careful physical examination. Molecular genetics is playing an increasing role in the evaluation of children with single-suture fusion.
Authors: Sarah S Park; Richard P Beyer; Matthew D Smyth; Christine M Clarke; Andrew E Timms; Theo K Bammler; Brendan D Stamper; Brigham H Mecham; Jennifer A Gustafson; Michael L Cunningham Journal: Bone Date: 2015-03-07 Impact factor: 4.398
Authors: Alexander H Sun; Jeffrey Eilbott; Carolyn Chuang; Jenny F Yang; Eric D Brooks; Joel Beckett; Derek M Steinbacher; Kevin Pelphrey; John A Persing Journal: J Craniofac Surg Date: 2019-09 Impact factor: 1.046
Authors: Negar Homayounfar; Sarah S Park; Zahra Afsharinejad; Theodor K Bammler; James W MacDonald; Federico M Farin; Brigham H Mecham; Michael L Cunningham Journal: Arch Oral Biol Date: 2015-07-02 Impact factor: 2.633
Authors: Guido de Jong; Elmar Bijlsma; Jene Meulstee; Myrte Wennen; Erik van Lindert; Thomas Maal; René Aquarius; Hans Delye Journal: Sci Rep Date: 2020-09-18 Impact factor: 4.379