| Literature DB >> 18025115 |
G Chamilos1, R E Lewis, G Lamaris, T J Walsh, D P Kontoyiannis.
Abstract
Human polymorphonuclear neutrophils (HPMNs) displayed attenuated hyphal damage associated with impaired O(2)(-) release following exposure to Rhizopus oryzae versus that with Aspergillus fumigatus. Exposure of HPMNs to R. oryzae hyphae resulted in upregulation in Toll-like receptor 2 mRNA and a robust proinflammatory gene expression with rapid (1-h) induction of NF-kappaB pathway-related genes.Entities:
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Year: 2007 PMID: 18025115 PMCID: PMC2224765 DOI: 10.1128/AAC.01136-07
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191