Literature DB >> 1801734

Tight-binding inhibition of cathepsin S by cystatins.

D Brömme1, R Rinne, H Kirschke.   

Abstract

Human cystatins A, B and C were purified, and their inhibition efficiency was tested with the cysteine proteinase cathepsin S. Cathepsin S was strongly inhibited by cystatins A and B in the subnanomolar range and by cystatin C in the picomolar range. Two steps of inhibition of cathepsin S by the cystatins which involve slow binding are discussed.

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Year:  1991        PMID： 1801734

Source DB:  PubMed          Journal:  Biomed Biochim Acta        ISSN： 0232-766X


  8 in total

1.  Rhabdovirus-induced apoptosis in a fish cell line is inhibited by a human endogenous acid cysteine proteinase inhibitor.

Authors:  H V Björklund; T R Johansson; A Rinne
Journal:  J Virol       Date:  1997-07       Impact factor: 5.103

2.  Pharmacokinetics and pharmacodynamics of the cathepsin S inhibitor, LY3000328, in healthy subjects.

Authors:  Christopher D Payne; Mark A Deeg; Melanie Chan; Lai Hock Tan; Elizabeth Smith LaBell; Tong Shen; David J DeBrota
Journal:  Br J Clin Pharmacol       Date:  2014-12       Impact factor: 4.335

3.  Purification and characterization of a new cystatin inhibitor from Taiwan cobra (Naja naja atra) venom.

Authors:  M Brillard-Bourdet; V Nguyên; M Ferrer-di Martino; F Gauthier; T Moreau
Journal:  Biochem J       Date:  1998-04-01       Impact factor: 3.857

4.  Modification of cystatin C activity by bacterial proteinases and neutrophil elastase in periodontitis.

Authors:  M Abrahamson; M Wikström; J Potempa; S Renvert; A Hall
Journal:  Mol Pathol       Date:  1997-12

5.  Concentrations of lysosomal cysteine proteases are decreased in renal cell carcinoma compared with normal kidney.

Authors:  H Kirschke; T Clausen; B Göhring; D Günther; E Heucke; F Laube; E Löwe; H Neef; H Papesch; S Peinze; G Plehn; U Rebmann; A Rinne; R Rüdrich; E Weber
Journal:  J Cancer Res Clin Oncol       Date:  1997       Impact factor: 4.553

Review 6.  Molecular background of progressive myoclonus epilepsy.

Authors:  Anna-Elina Lehesjoki
Journal:  EMBO J       Date:  2003-07-15       Impact factor: 11.598

7.  Increased expression of elastolytic cysteine proteases, cathepsins S and K, in the neointima of balloon-injured rat carotid arteries.

Authors:  Xian Wu Cheng; Masafumi Kuzuya; Takeshi Sasaki; Koji Arakawa; Shigeru Kanda; Daigo Sumi; Teruhiko Koike; Keiko Maeda; Norika Tamaya-Mori; Guo-Ping Shi; Noboru Saito; Akihisa Iguchi
Journal:  Am J Pathol       Date:  2004-01       Impact factor: 4.307

8.  Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB.

Authors:  Véronique Brault; Benoît Martin; Nathalie Costet; Jean-Charles Bizot; Yann Hérault
Journal:  PLoS One       Date:  2011-11-30       Impact factor: 3.240
  8 in total

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