Literature DB >> 18007055

Purification, crystallization and initial crystallographic characterization of brazil-nut allergen Ber e 2.

Feng Guo1, Tengchuan Jin, Andrew Howard, Yu Zhu Zhang.   

Abstract

Peanut and tree-nut allergies have attracted considerable attention because of their frequency and their lifelong persistence. Brazil-nut (Bertholletia excelsa) allergies have been well documented and the 11S legumin-like seed storage protein Ber e 2 (excelsin) is one of the two known brazil-nut allergens. In this study, Ber e 2 was extracted from brazil-nut kernels and purified to high purity by crystalline precipitation and gel-filtration chromatography. Well diffracting single crystals were obtained using the hanging-drop vapour-diffusion method. A molecular-replacement structural solution has been obtained. Refinement of the structure is currently under way.

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Year:  2007        PMID： 18007055      PMCID： PMC2339761          DOI： 10.1107/S1744309107051445

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN： 1744-3091


  26 in total

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2.  Purification and crystallization of Cor a 9, a major hazelnut allergen.

Authors:  Feng Guo; Mahendra H Kothary; Yang Wang; Xiaoping Yu; Andrew J Howard; Tong-Jen Fu; Yu-Zhu Zhang
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