Literature DB >> 18001850

Severe or lethal toxicities upon capecitabine intake: is DPYD genetic polymorphism the ideal culprit?

Cédric Mercier, Joseph Ciccolini.   

Abstract

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Year:  2007        PMID: 18001850     DOI: 10.1016/j.tips.2007.09.009

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN: 0165-6147            Impact factor:   14.819


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  8 in total

1.  Beating the odds: efficacy and toxicity of dihydropyrimidine dehydrogenase-driven adaptive dosing of 5-FU in patients with digestive cancer.

Authors:  Manon Launay; Laetitia Dahan; Manon Duval; Anne Rodallec; Gérard Milano; Muriel Duluc; Bruno Lacarelle; Joseph Ciccolini; Jean-Francois Seitz
Journal:  Br J Clin Pharmacol       Date:  2015-11-28       Impact factor: 4.335

Review 2.  Integrating pharmacogenetics into gemcitabine dosing--time for a change?

Authors:  Joseph Ciccolini; Cédric Mercier; Laetitia Dahan; Nicolas André
Journal:  Nat Rev Clin Oncol       Date:  2011-02-08       Impact factor: 66.675

3.  UPFRONT DPD DEFICIENCY DETECTION TO SECURE 5-FU ADMINISTRATION: PART 2- APPLICATION TO HEAD-AND-NECK CANCER PATIENTS.

Authors:  Manon Launay; Joseph Ciccolini; Claire Fournel; Carmelo Blanquicett; Charlotte Dupuis; Nicolas Fakhry; Florence Duffaud; Sébastien Salas; Bruno Lacarelle
Journal:  Clin Cancer Drugs       Date:  2017

4.  Pharmacokinetics of orally administered uracil in healthy volunteers and in DPD-deficient patients, a possible tool for screening of DPD deficiency.

Authors:  Maurice C van Staveren; Barbara Theeuwes-Oonk; Henk Jan Guchelaar; André B P van Kuilenburg; Jan Gerard Maring
Journal:  Cancer Chemother Pharmacol       Date:  2011-05-18       Impact factor: 3.333

5.  Heparin-induced thrombocytopenia in a patient with colon cancer.

Authors:  Ajaz Nabi Koul; Ridwana Ahad
Journal:  Indian J Med Paediatr Oncol       Date:  2013-10

6.  Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

Authors:  Marzia Del Re; Antonello Di Paolo; Ron H van Schaik; Guido Bocci; Paolo Simi; Alfredo Falcone; Romano Danesi
Journal:  EPMA J       Date:  2010-07-25       Impact factor: 6.543

7.  Discovery of novel mutations in the dihydropyrimidine dehydrogenase gene associated with toxicity of fluoropyrimidines and viewpoint on preemptive pharmacogenetic screening in patients.

Authors:  Marzia Del Re; Angela Michelucci; Angelo Di Leo; Maurizio Cantore; Roberto Bordonaro; Paolo Simi; Romano Danesi
Journal:  EPMA J       Date:  2015-09-02       Impact factor: 6.543

8.  Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity.

Authors:  Wen Wee Ma; Muhammad Wasif Saif; Bassel F El-Rayes; Marwan G Fakih; Thomas H Cartwright; James A Posey; Thomas R King; Reid W von Borstel; Michael K Bamat
Journal:  Cancer       Date:  2016-09-13       Impact factor: 6.860

  8 in total

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