OBJECTIVE: To estimate the individual- and population-level impact of major chronic conditions on health-related quality of life (HRQoL) at different ages, to test whether the HRQoL impact of conditions varies with age, and to predict future changes of quality-adjusted life years (QALYs) lost due to morbidity. STUDY DESIGN AND SETTING: HRQoL was measured using two preference-based instruments, the 15D and the EQ-5D, in a representative sample of 8,028 Finns. Information on chronic somatic conditions was obtained by interviews. Psychiatric disorders were diagnosed using a structured interview (Munich version of the Composite International Diagnostic Interview). RESULTS: The impact of chronic conditions on HRQoL increased fourfold when comparing people aged 30-44 years to people over 75 years. This was mostly due to increase in prevalence, but the severity of some conditions also varied with age. Musculoskeletal disorders had the largest and rather stable impact across ages on the population level. Psychiatric disorders placed the largest burden on HRQoL at 30-44 years, but their impact declined after 55 years. The aging of the Finnish population was predicted to increase annual QALYs lost due to morbidity by one quarter by year 2040. CONCLUSION: The impact of conditions on HRQoL varied with age for each condition.
OBJECTIVE: To estimate the individual- and population-level impact of major chronic conditions on health-related quality of life (HRQoL) at different ages, to test whether the HRQoL impact of conditions varies with age, and to predict future changes of quality-adjusted life years (QALYs) lost due to morbidity. STUDY DESIGN AND SETTING: HRQoL was measured using two preference-based instruments, the 15D and the EQ-5D, in a representative sample of 8,028 Finns. Information on chronic somatic conditions was obtained by interviews. Psychiatric disorders were diagnosed using a structured interview (Munich version of the Composite International Diagnostic Interview). RESULTS: The impact of chronic conditions on HRQoL increased fourfold when comparing people aged 30-44 years to people over 75 years. This was mostly due to increase in prevalence, but the severity of some conditions also varied with age. Musculoskeletal disorders had the largest and rather stable impact across ages on the population level. Psychiatric disorders placed the largest burden on HRQoL at 30-44 years, but their impact declined after 55 years. The aging of the Finnish population was predicted to increase annual QALYs lost due to morbidity by one quarter by year 2040. CONCLUSION: The impact of conditions on HRQoL varied with age for each condition.
Authors: Tarja H Välimäki; Janne A Martikainen; Kristiina Hongisto; Saku Väätäinen; Harri Sintonen; Anne M Koivisto Journal: Qual Life Res Date: 2015-09-09 Impact factor: 4.147
Authors: Luke Mondor; Colleen J Maxwell; Susan E Bronskill; Andrea Gruneir; Walter P Wodchis Journal: Qual Life Res Date: 2016-04-06 Impact factor: 4.147
Authors: Saku Väätäinen; Henri Tuomilehto; Jouko Saramies; Jaakko Tuomilehto; Hannu Uusitalo; Esko Hussi; Sirkka Keinänen-Kiukaanniemi; Janne Martikainen Journal: Qual Life Res Date: 2013-04-03 Impact factor: 4.147
Authors: Colleen J Maxwell; Jian Kang; Jennifer D Walker; Jenny X Zhang; David B Hogan; David H Feeny; Walter P Wodchis Journal: Health Qual Life Outcomes Date: 2009-09-02 Impact factor: 3.186
Authors: Maria D Antonopoulou; Athanasios K Alegakis; Alexander G Hadjipavlou; Christos D Lionis Journal: BMC Musculoskelet Disord Date: 2009-11-20 Impact factor: 2.362