Literature DB >> 17993533

LmrR is a transcriptional repressor of expression of the multidrug ABC transporter LmrCD in Lactococcus lactis.

Herfita Agustiandari1, Jacek Lubelski, H Bart van den Berg van Saparoea, Oscar P Kuipers, Arnold J M Driessen.   

Abstract

LmrCD is an ABC-type multidrug transporter in Lactococcus lactis. LmrR encodes a putative transcriptional regulator. In a DeltalmrR strain, lmrCD is up-regulated. LmrR binds the promoter region of lmrCD and interacts with drugs that cause lmrCD up-regulation. This suggests that LmrR is a drug-dependent transcriptional regulator of lmrCD expression.

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Year:  2007        PMID： 17993533      PMCID： PMC2223683          DOI： 10.1128/JB.01151-07

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  29 in total

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