OBJECTIVE: To assess whether pregnancy history can predict the occurrence of a spontaneous ongoing pregnancy in subfertile couples. DESIGN: Prospective cohort study. SETTING: Thirty fertility centers in the Netherlands. PATIENT(S): Subfertile, ovulatory women with at least one patent tube and male partners without severely impaired semen quality. INTERVENTION(S): Fertility work-up, including a detailed pregnancy history. MAIN OUTCOME MEASURE(S): Spontaneous ongoing pregnancy. RESULT(S): We included 4445 couples, of whom 793 (18%) had a spontaneous ongoing pregnancy within 1 year of follow-up. Previous live birth and miscarriage in current partnership were both associated with higher fecundity as compared with primary infertility (hazard rate ratios for spontaneous pregnancy [HR] 1.4; 95% CI, 1.2-1.7 and 1.3; 95% CI, 1.0-1.5, respectively). Pregnancies in a woman's previous partnerships did not affect the fecundity of the couple. A pregnancy in a previous partnership of the male partner was associated with lower fecundity (HR 0.76; 95% CI, 0.58-0.99). A previous pregnancy after fertility treatment also was associated with lower fecundity (HR 0.52; 95% CI, 0.30-0.90). CONCLUSION(S): Accurate prediction of the future fertility of a couple requires an exact assessment of the fertility history of both partners.
OBJECTIVE: To assess whether pregnancy history can predict the occurrence of a spontaneous ongoing pregnancy in subfertile couples. DESIGN: Prospective cohort study. SETTING: Thirty fertility centers in the Netherlands. PATIENT(S): Subfertile, ovulatory women with at least one patent tube and male partners without severely impaired semen quality. INTERVENTION(S): Fertility work-up, including a detailed pregnancy history. MAIN OUTCOME MEASURE(S): Spontaneous ongoing pregnancy. RESULT(S): We included 4445 couples, of whom 793 (18%) had a spontaneous ongoing pregnancy within 1 year of follow-up. Previous live birth and miscarriage in current partnership were both associated with higher fecundity as compared with primary infertility (hazard rate ratios for spontaneous pregnancy [HR] 1.4; 95% CI, 1.2-1.7 and 1.3; 95% CI, 1.0-1.5, respectively). Pregnancies in a woman's previous partnerships did not affect the fecundity of the couple. A pregnancy in a previous partnership of the male partner was associated with lower fecundity (HR 0.76; 95% CI, 0.58-0.99). A previous pregnancy after fertility treatment also was associated with lower fecundity (HR 0.52; 95% CI, 0.30-0.90). CONCLUSION(S): Accurate prediction of the future fertility of a couple requires an exact assessment of the fertility history of both partners.
Authors: James F Smith; Michael L Eisenberg; Susan G Millstein; Robert D Nachtigall; Natalia Sadetsky; Marcelle I Cedars; Patricia P Katz Journal: Fertil Steril Date: 2010-07-25 Impact factor: 7.329
Authors: Bernice M Hoenderboom; Jan E A M van Bergen; Nicole H T M Dukers-Muijrers; Hannelore M Götz; Christian J P A Hoebe; Henry J C de Vries; Ingrid V F van den Broek; Frank de Vries; Jolande A Land; Marianne A B van der Sande; Servaas A Morré; Birgit H B van Benthem Journal: Sex Transm Dis Date: 2020-11 Impact factor: 3.868