| Literature DB >> 17977991 |
Renata L Guerra1, James F Baker, Roya Alborz, Derek T Armstrong, Julia A Kiehlbauch, Marcus B Conde, Susan E Dorman, Nancy M Hooper.
Abstract
Specimen dilution has been proposed as a strategy to minimize amplified Mycobacterium tuberculosis direct (MTD) test inhibition (N. Pollock, J. Westerling, and A. Sloutsky, Am. J. Clin. Pathol. 126:142-147, 2006; A. Sloutsky, L. L. Han, and B. G. Werner, J. Clin. Microbiol. 42:1547-1551, 2004). We evaluated the impact of respiratory specimen dilution on MTD test accuracy in a public health laboratory. The difference in MTD test sensitivity between the dilution and conventional methods was 15.9% (P = 0.001) for smear microscopy-positive specimens and -3.6% (P = 0.38) for smear microscopy-negative specimens.Entities:
Mesh:
Year: 2007 PMID: 17977991 PMCID: PMC2224278 DOI: 10.1128/JCM.01313-07
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948