W Robert Bell1, W Richard Green, Morton F Goldberg. 1. Eye Pathology Laboratory, Department of Pathology, Wilmer Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
Abstract
OBJECTIVE: To report the ocular histopathologic features of a 55-year-old patient with incontinentia pigmenti retinopathy. DESIGN: Observational case report. PARTICIPANT: A 55-year-old patient with incontinentia pigmenti retinopathy. METHODS: Examination of eyes by light microscopy and retinal trypsin digestion. MAIN OUTCOME MEASURES: Clinical and histopathological findings. RESULTS: Histopathologic examination disclosed inner retinal ischemic atrophy, capillary beading, arteriolar-venous anastomoses, preretinal neovascularization, vasculopathy located at the junction of central vascular and peripheral avascular retina, retinal tears, and tractional retinoschisis. CONCLUSIONS: Patients with retinal manifestations of incontinentia pigmenti may progress to proliferative vitreoretinopathy or retinal detachment and should be observed closely over the course of their lifetime.
OBJECTIVE: To report the ocular histopathologic features of a 55-year-old patient with incontinentia pigmenti retinopathy. DESIGN: Observational case report. PARTICIPANT: A 55-year-old patient with incontinentia pigmenti retinopathy. METHODS: Examination of eyes by light microscopy and retinal trypsin digestion. MAIN OUTCOME MEASURES: Clinical and histopathological findings. RESULTS: Histopathologic examination disclosed inner retinal ischemic atrophy, capillary beading, arteriolar-venous anastomoses, preretinal neovascularization, vasculopathy located at the junction of central vascular and peripheral avascular retina, retinal tears, and tractional retinoschisis. CONCLUSIONS:Patients with retinal manifestations of incontinentia pigmenti may progress to proliferative vitreoretinopathy or retinal detachment and should be observed closely over the course of their lifetime.
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