| Literature DB >> 17973330 |
Joerg Mueller, Inger M Skogseid, Reiner Benecke, Andreas Kupsch, Thomas Trottenberg, Werner Poewe, Gerd H Schneider, Wilhelm Eisner, Alexander Wolters, J U Müller, Günther Deuschl, Marcus O Pinsker, Geir K Roeste, Juliane Vollmer-Haase, Angela Brentrup, Martin Krause, Volker Tronnier, Alfons Schnitzler, Jüergen Voges, Guido Nikkhah, Jan Vesper, Markus Naumann, Jens Volkmann.
Abstract
As part of the first randomized, sham-stimulation controlled trial on deep brain stimulation (DBS) in primary segmental or generalized dystonia, health-related quality of life (HRQoL) was assessed by SF-36. After the 3-month sham-controlled phase, significant HRQoL improvement occurred only in the active-stimulation group. The open-label extension phase resulted in a significant improvement in all SF-36 domains following 6 months of neurostimulation. These results demonstrate a favorable impact of DBS on HRQoL in primary dystonia. 2007 Movement Disorder SocietyEntities:
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Year: 2008 PMID： 17973330 DOI： 10.1002/mds.21783
Source DB: PubMed Journal: Mov Disord ISSN： 0885-3185 Impact factor: 10.338