Literature DB >> 17965475

Two new cytotoxic quinone type compounds from the halotolerant fungus Aspergillus variecolor.

Wenliang Wang1, Tianjiao Zhu, Hongwen Tao, Zhenyu Lu, Yuchun Fang, Qianqun Gu, Weiming Zhu.   

Abstract

Two new quinone type compounds, variecolorquinones A (1) and B (2) together with eleven known related compounds 3 approximately 13 have been isolated from the metabolites produced by the halotolerant fungal strain Aspergillus variecolor B-17. The structures of 1 and 2 were determined by spectroscopic methods. 1 exhibited selective cytotoxicity against A-549 cells with the IC50 values of 3.0 microM. 2 showed cytotoxicity against HL60 and P388 cells with the IC50 values of 1.3 and 3.7 microM, respectively.

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Year:  2007        PMID： 17965475     DOI： 10.1038/ja.2007.77

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

1.  Antimicrobial Agents Produced by Marine Aspergillus terreus var. africanus Against Some Virulent Fish Pathogens.

Authors:  Khouloud M Barakat; Yousry M Gohar
Journal:  Indian J Microbiol       Date:  2012-02-17       Impact factor: 2.461

Review 2.  Anthraquinones and Their Analogues from Marine-Derived Fungi: Chemistry and Biological Activities.

Authors:  Salar Hafez Ghoran; Fatemeh Taktaz; Seyed Abdulmajid Ayatollahi; Anake Kijjoa
Journal:  Mar Drugs       Date:  2022-07-25       Impact factor: 6.085

3.  Polyphasic taxonomy of Aspergillus section Aspergillus (formerly Eurotium), and its occurrence in indoor environments and food.

Authors:  A J Chen; V Hubka; J C Frisvad; C M Visagie; J Houbraken; M Meijer; J Varga; R Demirel; Ž Jurjević; A Kubátová; F Sklenář; Y G Zhou; R A Samson
Journal:  Stud Mycol       Date:  2017-07-12       Impact factor: 16.097

4.  1,6-Dihydr-oxy-3-hydroxy-methyl-8-methoxy-anthracene-9,10-dione monohydrate.

Authors:  Wen-Liang Wang; Wei Sun; Qian-Qun Gu; Wei-Ming Zhu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2007-12-21

Review 5.  Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities.

Authors:  Mireille Fouillaud; Mekala Venkatachalam; Emmanuelle Girard-Valenciennes; Yanis Caro; Laurent Dufossé
Journal:  Mar Drugs       Date:  2016-03-25       Impact factor: 5.118

Review 6.  Chemical diversity, medicinal potentialities, biosynthesis, and pharmacokinetics of anthraquinones and their congeners derived from marine fungi: a comprehensive update.

Authors:  Mohamed Sebak; Fatma Molham; Claudio Greco; Mohamed A Tammam; Mansour Sobeh; Amr El-Demerdash
Journal:  RSC Adv       Date:  2022-09-01       Impact factor: 4.036

Review 7.  Novel Natural Products from Extremophilic Fungi.

Authors:  Xuan Zhang; Shou-Jie Li; Jin-Jie Li; Zi-Zhen Liang; Chang-Qi Zhao
Journal:  Mar Drugs       Date:  2018-06-04       Impact factor: 5.118

Review 8.  Fungal Pigments and Their Roles Associated with Human Health.

Authors:  Lan Lin; Jianping Xu
Journal:  J Fungi (Basel)       Date:  2020-11-12
  8 in total

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