Literature DB >> 17960103

New polyhydroxylated furostanol saponins with inhibitory action against NO production from Tupistra chinensis rhizomes.

Lan-Lan Xu1, Kun Zou, Jun-Zhi Wang, Jun Wu, Yuan Zhou, Fei-Jun Dan, Jing Yang.   

Abstract

Two furostanol saponins were obtained from the rhizomes of Tupistra chinensis Bak. Their structures were determined as 5beta-furost-delta(25(27))-en-1beta,2beta,3beta,4beta,5beta,7alpha,22xi,26-octaol-6-one-26-O-beta-D-glucopyranoside (1) and 5beta-furost-delta(25(27))-en-1beta,2beta,3beta,4beta,5beta,6beta,7alpha,22xi,26-nonaol-26-O-beta-D-glucopyranoside (2), on the basis of chemical and spectroscopic evidence. Both compounds displayed marked inhibitory action against NO production in rat abdomen macrophages induced by lipopolysaccharide (LPS) at 40 microg/mL.

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Year:  2007        PMID： 17960103      PMCID： PMC6149104          DOI： 10.3390/12082029

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  11 in total

1.  Chemical constituents of Tupistra chinensis rhizomes.

Authors:  Wen-Bin Pan; Li-Mei Wei; Li-Lan Wei; Yang-Chang Wu
Journal:  Chem Pharm Bull (Tokyo)       Date:  2006-07       Impact factor: 1.645

2.  Spirostanol sapogenins from the underground parts of Tupistra chinensis.

Authors:  W B Pan; F R Chang; Y C Wu
Journal:  Chem Pharm Bull (Tokyo)       Date:  2000-09       Impact factor: 1.645

3.  Lipoteichoic acid-induced nitric oxide synthase expression in RAW 264.7 macrophages is mediated by cyclooxygenase-2, prostaglandin E2, protein kinase A, p38 MAPK, and nuclear factor-kappaB pathways.

Authors:  Yau-Chong Chang; Pei-Chih Li; Bing-Chang Chen; Ming-Shyan Chang; Jui-Ling Wang; Wen-Ta Chiu; Chien-Huang Lin
Journal:  Cell Signal       Date:  2005-11-11       Impact factor: 4.315

4.  An 18-norspirostanol saponin with inhibitory action against COX-2 production from the underground part of Trillium tschonoskii.

Authors:  Junzhi Wang; Kun Zou; Yanming Zhang; Chuang Liu; Jun Wu; Yuan Zhou; Feijun Dan; Yaxiong Zhang
Journal:  Chem Pharm Bull (Tokyo)       Date:  2007-04       Impact factor: 1.645

5.  The role of IFN-alpha and nitric oxide in the release of HMGB1 by RAW 264.7 cells stimulated with polyinosinic-polycytidylic acid or lipopolysaccharide.

Authors:  Weiwen Jiang; David S Pisetsky
Journal:  J Immunol       Date:  2006-09-01       Impact factor: 5.422

6.  Diastereoisomeric saponins from Albizia julibrissin.

Authors:  Kun Zou; Wen-yong Tong; Hong Liang; Jing-rong Cui; Guang-zhong Tu; Yu-ying Zhao; Ru-yi Zhang
Journal:  Carbohydr Res       Date:  2005-05-23       Impact factor: 2.104

7.  Steroidal saponins from the leaves of Cordyline stricta.

Authors:  Y Mimaki; M Kuroda; Y Takaashi; Y Sashida
Journal:  Phytochemistry       Date:  1998-01       Impact factor: 4.072

8.  New flavans, spirostanol sapogenins, and a pregnane genin from Tupistra chinensis and their cytotoxicity.

Authors:  Wen-Bin Pan; Fang-Rong Chang; Li-Mei Wei; Yang-Chang Wu
Journal:  J Nat Prod       Date:  2003-02       Impact factor: 4.050

Review 9.  Nitric oxide: comparative synthesis and signaling in animal and plant cells.

Authors:  D Wendehenne; A Pugin; D F Klessig; J Durner
Journal:  Trends Plant Sci       Date:  2001-04       Impact factor: 18.313

10.  In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production.

Authors:  Shing-Chuan Shen; Woan-Ruoh Lee; Hui-Yi Lin; Ho-Chun Huang; Ching-Huai Ko; Ling-Ling Yang; Yen-Chou Chen
Journal:  Eur J Pharmacol       Date:  2002-06-20       Impact factor: 4.432
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  1 in total

1.  Antiproliferative and anti-inflammatory polyhydroxylated spirostanol saponins from Tupistra chinensis.

Authors:  Limin Xiang; Xiaomin Yi; Yihai Wang; Xiangjiu He
Journal:  Sci Rep       Date:  2016-08-17       Impact factor: 4.379
  1 in total

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