| Literature DB >> 17409572 |
Junzhi Wang1, Kun Zou, Yanming Zhang, Chuang Liu, Jun Wu, Yuan Zhou, Feijun Dan, Yaxiong Zhang.
Abstract
A novel 18-norspirostanol saponin (1), along with Trillenoside A (2), was obtained from the underground parts of Trillium tschonoskii MAXIM., collected in Shennongjia Forest District, China. Based on the chemical and spectroscopic evidences, their structures were determined as shown in Fig. 1. 1 and 2 displayed marked inhibitory action towards COX-2 production in macrophagocytes of the mouse abdominal cavity stimulated by LPS at 10 microg/ml.Entities:
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Year: 2007 PMID: 17409572 DOI: 10.1248/cpb.55.679
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN: 0009-2363 Impact factor: 1.645