PURPOSE: To study the long-term effect of being overweight on mortality in very elderly subjects. METHODS: The medical records of 470 inpatients (226 males) with a mean age of 81.5 +/- 7 years and hospitalized in an acute geriatric ward between 1999 and 2000 were reviewed for this study. Body mass index (BMI) at admission day was subdivided into quartiles: <22, 22-25, 25.01-28, and > or =28 kg/m(2). Patients were followed-up until August 31, 2004. Mortality data were taken from death certificates. RESULTS: During a mean follow-up of 3.46 +/- 1.87 years (median 4.2 years [range 1.6 to 5.34 years]), 248 patients died. Those who died had lower baseline BMI than those who survived (24.1 +/- 4.2 vs 26.3 +/- 4.6 kg/m(2); p < .0001). The age-adjusted mortality rate decreased from 24 to 9.6 per 100 patient-years from the highest to lowest BMI quartile (p < .001). BMI was associated with all-cause and cause-specific mortality even after controlling for sex. A multivariate Cox proportional hazards model identified that even after controlling for male gender, age, renal failure, and diabetes mellitus, which increased the risk of all-cause mortality, elevated BMI decreased the all-cause mortality risk. CONCLUSIONS: In very elderly subjects, elevated BMI was associated with reduced mortality risk.
PURPOSE: To study the long-term effect of being overweight on mortality in very elderly subjects. METHODS: The medical records of 470 inpatients (226 males) with a mean age of 81.5 +/- 7 years and hospitalized in an acute geriatric ward between 1999 and 2000 were reviewed for this study. Body mass index (BMI) at admission day was subdivided into quartiles: <22, 22-25, 25.01-28, and > or =28 kg/m(2). Patients were followed-up until August 31, 2004. Mortality data were taken from death certificates. RESULTS: During a mean follow-up of 3.46 +/- 1.87 years (median 4.2 years [range 1.6 to 5.34 years]), 248 patients died. Those who died had lower baseline BMI than those who survived (24.1 +/- 4.2 vs 26.3 +/- 4.6 kg/m(2); p < .0001). The age-adjusted mortality rate decreased from 24 to 9.6 per 100 patient-years from the highest to lowest BMI quartile (p < .001). BMI was associated with all-cause and cause-specific mortality even after controlling for sex. A multivariate Cox proportional hazards model identified that even after controlling for male gender, age, renal failure, and diabetes mellitus, which increased the risk of all-cause mortality, elevated BMI decreased the all-cause mortality risk. CONCLUSIONS: In very elderly subjects, elevated BMI was associated with reduced mortality risk.
Authors: Gregg C Fonarow; Preethi Srikanthan; Maria Rosa Costanzo; Guillermo B Cintron; Margarita Lopatin Journal: Am Heart J Date: 2007-01 Impact factor: 4.749
Authors: Amit Kumar; Amol M Karmarkar; Alai Tan; James E Graham; Christine M Arcari; Kenneth J Ottenbacher; Soham Al Snih Journal: Salud Publica Mex Date: 2015
Authors: A B Pedersen; D Cronin Fenton; M Nørgaard; N R Kristensen; B Kuno Møller; C Erikstrup Journal: Osteoporos Int Date: 2016-04-21 Impact factor: 4.507
Authors: Martica H Hall; Stephen F Smagula; Robert M Boudreau; Hilsa N Ayonayon; Suzanne E Goldman; Tamara B Harris; Barbara L Naydeck; Susan M Rubin; Laura Samuelsson; Suzanne Satterfield; Katie L Stone; Marjolein Visser; Anne B Newman Journal: Sleep Date: 2015-02-01 Impact factor: 5.849
Authors: Charles F Emery; Deborah Finkel; Margaret Gatz; Anna K Dahl Aslan Journal: J Gerontol B Psychol Sci Soc Sci Date: 2020-09-14 Impact factor: 4.077