Literature DB >> 10766250

Obesity as a medical problem.

P G Kopelman1.   

Abstract

Obesity is now so common within the world's population that it is beginning to replace undernutrition and infectious diseases as the most significant contributor to ill health. In particular, obesity is associated with diabetes mellitus, coronary heart disease, certain forms of cancer, and sleep-breathing disorders. Obesity is defined by a body-mass index (weight divided by square of the height) of 30 kg m(-2) or greater, but this does not take into account the morbidity and mortality associated with more modest degrees of overweight, nor the detrimental effect of intra-abdominal fat. The global epidemic of obesity results from a combination of genetic susceptibility, increased availability of high-energy foods and decreased requirement for physical activity in modern society. Obesity should no longer be regarded simply as a cosmetic problem affecting certain individuals, but an epidemic that threatens global well being.

Entities:  

Mesh:

Year:  2000        PMID: 10766250     DOI: 10.1038/35007508

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  1115 in total

Review 1.  Mechanisms of nutritional and hormonal regulation of lipogenesis.

Authors:  S Kersten
Journal:  EMBO Rep       Date:  2001-04       Impact factor: 8.807

2.  Induction of Bach1 and ARA70 gene expression at an early stage of adipocyte differentiation of mouse 3T3-L1 cells.

Authors:  Makoto Nishizuka; Tomoko Tsuchiya; Tsutomu Nishihara; Masayoshi Imagawa
Journal:  Biochem J       Date:  2002-02-01       Impact factor: 3.857

3.  A genomewide linkage scan for quantitative-trait loci for obesity phenotypes.

Authors:  Hong-Wen Deng; Hongyi Deng; Yong-Jun Liu; Yao-Zhong Liu; Fu-Hua Xu; Hui Shen; Theresa Conway; Jin-Long Li; Qing-Yang Huang; K M Davies; Robert R Recker
Journal:  Am J Hum Genet       Date:  2002-03-28       Impact factor: 11.025

Review 4.  Animal models of postinfectious obesity: hypothesis and review.

Authors:  M J Lyons; K Nagashima; J B Zabriskie
Journal:  J Neurovirol       Date:  2002-02       Impact factor: 2.643

5.  Effect of obesity on alveolar bone loss in experimental periodontitis in Wistar rats.

Authors:  Giliano Nicolini Verzeletti; Eduardo José Gaio; Daniele Sigal Linhares; Cassiano Kuchenbecker Rösing
Journal:  J Appl Oral Sci       Date:  2012 Mar-Apr       Impact factor: 2.698

6.  Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice.

Authors:  Ganesh V Halade; Amina El Jamali; Paul J Williams; Roberto J Fajardo; Gabriel Fernandes
Journal:  Exp Gerontol       Date:  2010-10-12       Impact factor: 4.032

7.  Risk-assessment and coping strategies segregate with divergent intrinsic aerobic capacity in rats.

Authors:  Paul R Burghardt; Shelly B Flagel; Kyle J Burghardt; Steven L Britton; Lauren Gerard-Koch; Stanley J Watson; Huda Akil
Journal:  Neuropsychopharmacology       Date:  2010-10-06       Impact factor: 7.853

8.  Piceatannol Reduces Fat Accumulation in Caenorhabditis elegans.

Authors:  Peiyi Shen; Yiren Yue; Kee-Hong Kim; Yeonhwa Park
Journal:  J Med Food       Date:  2017-05-17       Impact factor: 2.786

9.  Ablation of TrkB expression in RGS9-2 cells leads to hyperphagic obesity.

Authors:  Guey-Ying Liao; Yuqing Li; Baoji Xu
Journal:  Mol Metab       Date:  2013-08-09       Impact factor: 7.422

10.  Longitudinal changes in body mass and composition in survivors of childhood hematologic malignancies after allogeneic hematopoietic stem-cell transplantation.

Authors:  Hiroto Inaba; Jie Yang; Sue C Kaste; Christine M Hartford; Megan S Motosue; Wassim Chemaitilly; Brandon M Triplett; David R Shook; Ching-Hon Pui; Wing Leung
Journal:  J Clin Oncol       Date:  2012-10-01       Impact factor: 44.544

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.