Literature DB >> 17955274

A 43-year-old man with reduced visual acuity and normal fundus: occult macular dystrophy--case report.

Wojciech Lubiński1, Wojciech Gosławski, Krzysztof Penkala, Monika Drobek-Słowik, Danuta Karczewicz.   

Abstract

PURPOSE: Occult macular dystrophy (OMD) is an unusual, inherited macular dystrophy characterized by a slowly progressive decline of visual acuity with normal fundus and fluorescein angiography (FA). The authors present a 43-year-old man who was diagnosed as having OMD because of the results of electrophysiological, psychophysical, optical coherence tomography (OCT) tests.
METHODS: Routine ophthalmological evaluation, FA, visual field tests, electroretinographic examinations (EOG, ERG, PERG and mfERG recordings according to ISCEV standards) and foveal thickness measurements (OCT) were performed.
RESULTS: Funduscopic examinations, FA, full field ERG as well as PERG results were all normal. In both eyes, the abnormalities were observed in static perimetry (relative central scotomas), mfERG (significant reduction of P1 amplitude in the central retinas) and OCT (significantly thinner foveal thickness).
CONCLUSIONS: A new case with OMD is added to preceding reports. The mfERG and OCT tests are important in detection of OMD patients. It can help in differential diagnosis of amblyopia, optic nerve diseases and non-organic visual disorders.

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Year:  2007        PMID: 17955274     DOI: 10.1007/s10633-007-9086-5

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN: 0012-4486            Impact factor:   2.379


  21 in total

1.  Standard for pattern electroretinography. International Society for Clinical Electrophysiology of Vision.

Authors:  M Bach; M Hawlina; G E Holder; M F Marmor; T Meigen; Y Miyake
Journal:  Doc Ophthalmol       Date:  2000-07       Impact factor: 2.379

2.  Foveal cone electroretinograms in patients with central visual loss of unexplained etiology.

Authors:  G P Matthews; M A Sandberg; E L Berson
Journal:  Arch Ophthalmol       Date:  1992-11

Review 3.  The multifocal electroretinogram.

Authors:  Donald C Hood; Jeffrey G Odel; Candice S Chen; Bryan J Winn
Journal:  J Neuroophthalmol       Date:  2003-09       Impact factor: 3.042

4.  Standard for clinical electroretinography (2004 update).

Authors:  Michael F Marmor; Graham E Holder; Mathias W Seeliger; Shuichi Yamamoto
Journal:  Doc Ophthalmol       Date:  2004-03       Impact factor: 2.379

5.  Occult macular dystrophy in an 11 year old boy.

Authors:  M Kondo; S Ueno; C-H Piao; Y Ito; H Terasaki; Y Miyake
Journal:  Br J Ophthalmol       Date:  2004-12       Impact factor: 4.638

6.  Spatial tuning of the pattern ERG across temporal frequency.

Authors:  T Berninger; R P Schuurmans
Journal:  Doc Ophthalmol       Date:  1985-10-30       Impact factor: 2.379

7.  Multifocal electroretinogram in occult macular dystrophy.

Authors:  C H Piao; M Kondo; A Tanikawa; H Terasaki; Y Miyake
Journal:  Invest Ophthalmol Vis Sci       Date:  2000-02       Impact factor: 4.799

8.  A case of occult macular dystrophy accompanying normal-tension glaucoma.

Authors:  Makoto Nakamura; Akiyasu Kanamori; Ryu Seya; Hidetaka Maeda; Akira Negi
Journal:  Am J Ophthalmol       Date:  2003-05       Impact factor: 5.258

9.  Peripheral cone dystrophy: a variant of cone dystrophy with predominant dysfunction in the peripheral cone system.

Authors:  Mineo Kondo; Yozo Miyake; Nagako Kondo; Shinji Ueno; Hideo Takakuwa; Hiroko Terasaki
Journal:  Ophthalmology       Date:  2004-04       Impact factor: 12.079

10.  ISCEV standard for clinical pattern electroretinography--2007 update.

Authors:  Graham E Holder; Mitchell G Brigell; Marko Hawlina; Thomas Meigen; Michael Bach
Journal:  Doc Ophthalmol       Date:  2007-04-14       Impact factor: 2.379

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  2 in total

Review 1.  Occult macular dystrophy.

Authors:  Yozo Miyake; Kazushige Tsunoda
Journal:  Jpn J Ophthalmol       Date:  2015-02-10       Impact factor: 2.447

2.  Imaging and the perspective of clinical electrophysiology.

Authors:  Ulrich Kellner
Journal:  Doc Ophthalmol       Date:  2007-12-19       Impact factor: 2.379

  2 in total

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