Literature DB >> 17952068

Sex chromosome complement regulates habit formation.

Jennifer J Quinn1, Paul K Hitchcott, Elizabeth A Umeda, Arthur P Arnold, Jane R Taylor.   

Abstract

Sex differences in brain function and behavior are regularly attributed to gonadal hormones. Some brain sexual dimorphisms, however, are direct actions of sex chromosome genes that are not mediated by gonadal hormones. We used mice in which sex chromosome complement (XX versus XY) and gonadal sex (ovaries versus testes) were independent, and found that XX mice showed faster food-reinforced instrumental habit formation than XY mice, regardless of gonadal phenotype.

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Year:  2007        PMID： 17952068     DOI： 10.1038/nn1994

Source DB:  PubMed          Journal:  Nat Neurosci        ISSN： 1097-6256            Impact factor:   24.884


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