Literature DB >> 17950603

Cytotoxic and apoptotic activities of novel amino analogues of boswellic acids.

Bhahwal A Shah1, Ajay Kumar, Pankaj Gupta, Madhunika Sharma, Vijay K Sethi, Ajit K Saxena, Jaswant Singh, Ghulam N Qazi, Subhash C Taneja.   

Abstract

4-Amino analogues prepared from beta-boswellic acid and 11-keto-beta-boswellic acid, wherein the carboxyl group in ursane nucleus was replaced by an amino function via Curtius reaction, displayed improved cytotoxicity than the parent molecules. The same molecules also exhibited apoptotic activity by inducing DNA fragmentation.

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Year:  2007        PMID： 17950603     DOI： 10.1016/j.bmcl.2007.10.011

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  10 in total

Review 1.  Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents.

Authors:  Reen-Yen Kuo; Keduo Qian; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal:  Nat Prod Rep       Date:  2009-08-13       Impact factor: 13.423

Review 2.  Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation.

Authors:  Wamidh H Talib; Izzeddin Alsalahat; Safa Daoud; Reem Fawaz Abutayeh; Asma Ismail Mahmod
Journal:  Molecules       Date:  2020-11-14       Impact factor: 4.411

3.  Evaluation of Cassia occidentalis for in vitro cytotoxicity against human cancer cell lines and antibacterial activity.

Authors:  Madhulika Bhagat; Ajit Kumar Saxena
Journal:  Indian J Pharmacol       Date:  2010-08       Impact factor: 1.200

4.  Antistaphylococcal and biofilm inhibitory activities of acetyl-11-keto-β-boswellic acid from Boswellia serrata.

Authors:  Alsaba F Raja; Furqan Ali; Inshad A Khan; Abdul S Shawl; Daljit S Arora; Bhahwal A Shah; Subhash C Taneja
Journal:  BMC Microbiol       Date:  2011-03-16       Impact factor: 3.605

5.  Acetyl-11-keto-β-boswellic acid (AKBA); targeting oral cavity pathogens.

Authors:  Alsaba F Raja; Furqan Ali; Inshad A Khan; Abdul S Shawl; Daljit S Arora
Journal:  BMC Res Notes       Date:  2011-10-13

6.  Synthesis and evaluation of flavanones as anticancer agents.

Authors:  Y Murti; P Mishra
Journal:  Indian J Pharm Sci       Date:  2014-03       Impact factor: 0.975

7.  Investigation of mitigating effect of colon-specific prodrugs of boswellic acid on 2,4,6-trinitrobenzene sulfonic acid-induced colitis in Wistar rats: Design, kinetics and biological evaluation.

Authors:  Ajinkya Sarkate; Suneela S Dhaneshwar
Journal:  World J Gastroenterol       Date:  2017-02-21       Impact factor: 5.742

8.  Chemical, molecular and structural studies of Boswellia species: β-Boswellic Aldehyde and 3-epi-11β-Dihydroxy BA as precursors in biosynthesis of boswellic acids.

Authors:  Ahmed Al-Harrasi; Najeeb Ur Rehman; Abdul Latif Khan; Muhammed Al-Broumi; Issa Al-Amri; Javid Hussain; Hidayat Hussain; René Csuk
Journal:  PLoS One       Date:  2018-06-18       Impact factor: 3.240

9.  Palmatine from Unexplored Rutidea parviflora Showed Cytotoxicity and Induction of Apoptosis in Human Ovarian Cancer Cells.

Authors:  Okiemute Rosa Johnson-Ajinwo; Alan Richardson; Wen-Wu Li
Journal:  Toxins (Basel)       Date:  2019-04-25       Impact factor: 4.546

10.  Synthesis and Biological Application of Isosteviol-Based 1,3-Aminoalcohols.

Authors:  Dániel Ozsvár; Viktória Nagy; István Zupkó; Zsolt Szakonyi
Journal:  Int J Mol Sci       Date:  2021-10-18       Impact factor: 5.923
  10 in total

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